Portal vein embolization with n-butyl-cyanoacrylate through an ipsilateral approach before major hepatectomy: single center analysis of 50 consecutive patients

dc.creatorLuz, José Hugo Mendes
dc.creatorLuz, Paula Mendes
dc.creatorBilhim, Tiago
dc.creatorMartin, Henrique Salas
dc.creatorGouveia, Hugo Rodrigues
dc.creatorCoimbra, Élia
dc.creatorGomes, Filipe Veloso
dc.creatorSouza, Roberto Romulo
dc.creatorFaria, Igor Murad
dc.creatorde Miranda, Tiago Nepomuceno
dc.date2018-04-12T16:01:33Z
dc.date2018-04-12T16:01:33Z
dc.date2017
dc.date.accessioned2023-09-26T20:08:02Z
dc.date.available2023-09-26T20:08:02Z
dc.identifierLUZ, José Hugo Mendes, et al. Portal vein embolization with n-butylcyanoacrylate through an ipsilateral approach before major hepatectomy: single center analysis of 50 consecutive patients. Cancer Imaging, v. 17, n. 25, 2017.
dc.identifier1470-7330
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/25819
dc.identifier10.1186/s40644-017-0127-3
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8849327
dc.descriptionPurpose: To evaluate the efficacy of portal vein embolization (PVE) with n-Butyl-cyanoacrylate (NBCA) through an ipsilateral approach before major hepatectomy. Secondary end-points were PVE safety, liver resection and patient outcome. Methods: Over a 5-year period 50 non-cirrhotic consecutive patients were included with primary or secondary liver cancer treatable by hepatectomy with a liver remnant (FLR) volume less than 25% or less than 40% in diseased livers. Results: There were 37 men and 13 women with a mean age of 57 years. Colorectal liver metastases were the most frequent tumor and patients were previously exposed to chemotherapy. FLR increased from 422 ml to 629 ml (P < 0.001) after PVE, corresponding to anincrease of 52%. The FLR ratio increased from 29.6% to 42.3% (P < 0.001). Kinetic growth rate was 2.98%/week. A negative association was observed between increase in the FLR and FLR ratio and FLR volume before PVE (P = 0.002). In 31 patients hepatectomy was accomplished and only one patient presented with liver insufficiency within 30 days after surgery. Conclusions: PVE with NBCA through an ipsilateral puncture is effective before major hepatectomy. Meticulous attention is needed especially near the end of the embolization procedure to avoid complications.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBioMed Central
dc.rightsopen access
dc.subjectPortal Vein
dc.subjectEmbolization
dc.subjectFuture liver remnant
dc.subjectExtended hepatectomy
dc.subjectHepatic Insufficiency
dc.subjectVeia Porta
dc.subjectInsuficiência Hepática
dc.titlePortal vein embolization with n-butyl-cyanoacrylate through an ipsilateral approach before major hepatectomy: single center analysis of 50 consecutive patients
dc.typeArticle


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