Polymerase chain reaction (PCR) is highly sensitive for diagnosis of mucosal leishmaniasis.

dc.creatorOliveira, Jene Greyce Souza de
dc.creatorNovais, Fernanda Oliveira
dc.creatorOliveira, Camila Indiani de
dc.creatorCruz Junior, Antonio Clementino da
dc.creatorCampos, Léon Fábio
dc.creatorRocha, Any V. da
dc.creatorBoaventura, Viviane Sampaio
dc.creatorNoronha, Almério Libório Lopes de
dc.creatorCosta, Jackson Mauricio Lopes
dc.creatorBarral, Aldina Maria Prado
dc.date2014-12-12T19:19:27Z
dc.date2014-12-12T19:19:27Z
dc.date2005
dc.date.accessioned2023-09-26T20:06:36Z
dc.date.available2023-09-26T20:06:36Z
dc.identifierOLIVEIRA, J. G. S. et al. Polymerase chain reaction (PCR) is highly sensitive for diagnosis of mucosal leishmaniasis. Acta Tropica, v. 94, n. 1, p. 55-59, 2005.
dc.identifier0001-706X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/9172
dc.identifier10.1016/j.actatropica.2004.12.003
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8848686
dc.descriptionWe evaluated the use of polymerase chain reaction (PCR) for diagnosis of mucosal leishmaniasis (ML) in an endemic area in Acre, Brazil, where Leishmania braziliensis is present. Leishmania DNA was detected 34 of 35 cases, yielding a positivity rate of 97.1%, which was higher than the positivity rates for all of the other diagnostic methods studied, namely Montenegro skin test (MST), anti-Leishmania serological testing and microscopic examination of lesion biopsy specimens. These findings have led us to propose guidelines for the diagnosis of ML that use PCR as the principal method of parasitological confirmation of cases.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectPolymerase chain reaction
dc.subjectLeishmania braziliensis
dc.subjectMucosal leishmaniasis
dc.subjectLeishmania braziliensis/genética
dc.subjectLeishmaniose Cutânea/diagnóstico
dc.subjectAdolescente
dc.subjectAdulto
dc.subjectIdoso
dc.subjectIdoso de 80 Anos ou mais
dc.subjectAnimais
dc.subjectAnticorpos Antiprotozoários/sangue
dc.subjectAntiprotozoários/uso terapêutico
dc.subjectBiópsia
dc.subjectBrasil
dc.subjectCriança
dc.subjectDNA de Protozoário/química
dc.subjectFeminino
dc.subjectTécnica Indireta de Fluorescência para Anticorpo
dc.subjectHumanos
dc.subjectLeishmaniose Cutânea/quimioterapia
dc.subjectMasculino
dc.subjectMeglumina/uso terapêutico
dc.subjectMeia-Idade
dc.subjectCompostos Organometálicos/uso terapêutico
dc.subjectSensibilidade e Especificidade
dc.subjectTestes cutâneos
dc.titlePolymerase chain reaction (PCR) is highly sensitive for diagnosis of mucosal leishmaniasis.
dc.typeArticle


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