Toll-Like Receptor-2-Mediated C-C Chemokine Receptor 3 and Eotaxin-Driven Eosinophil Influx Induced by Mycobacterium bovis BCG Pleurisy

dc.creatorD'Avila, Heloisa
dc.creatorAlmeida, Patrícia E.
dc.creatorRoque, Natália R.
dc.creatorFaria Neto, Hugo Caire C.
dc.creatorBozza, Patrícia T.
dc.date2020-04-20T19:08:11Z
dc.date2020-04-20T19:08:11Z
dc.date2007
dc.date.accessioned2023-09-26T20:06:24Z
dc.date.available2023-09-26T20:06:24Z
dc.identifierD`ÁVILA, Heloisa et al. Toll-Like Receptor-2-Mediated C-C Chemokine Receptor 3 and Eotaxin-Driven Eosinophil Influx Induced by Mycobacterium bovis BCG Pleurisy. Infection and Immunity, v. 75, n. 3, p. 1507-1522, Mar. 2007.
dc.identifier0019-9567
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/40900
dc.identifier10.1128/IAI.01326-06
dc.identifier1098-5522
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8848613
dc.descriptionAcesso aberto em 20/04/2020 - https://iai.asm.org/content/iai/75/3/1507.full.pdf
dc.descriptionAn acute and persistent eosinophil infiltration is observed during Mycobacterium bovis BCG pleural infection in mice. Eosinophil accumulation, lipid body formation, and eotaxin production were significantly reduced in BCG-infected Toll-like receptor-2 (TLR2)-deficient mice compared to wild-type mice. Neutralization of eotaxin or CCR3 drastically inhibited BCG-induced eosinophil accumulation and lipid body formation, indicating that BCG-induced eosinophil recruitment and activation is largely dependent of TLR2-mediated eotaxin generation.
dc.description2020-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.rightsopen access
dc.subjectInfluxo de Eosinófilos
dc.subjectEotaxina
dc.subjectMycobacterium bovis BCG Pleurisia
dc.subjectReceptor C-C Mediado por Quimiocina
dc.subjectToll-Like Receptor-2
dc.subjectMediated C-C Chemokine
dc.subjectMycobacterium bovis BCG Pleurisia
dc.subjectEosinophil Influx
dc.titleToll-Like Receptor-2-Mediated C-C Chemokine Receptor 3 and Eotaxin-Driven Eosinophil Influx Induced by Mycobacterium bovis BCG Pleurisy
dc.typeArticle


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