Aging reduces complexity of heart rate variability assessed by conditional entropy and symbolic analysis

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorTakahashi, Anielle C. M.
dc.creatorPorta, Alberto
dc.creatorMelo, Ruth C.
dc.creatorQuiterio, Robison J.
dc.creatorda Silva, Ester
dc.creatorBorghi-Silva, Audrey
dc.creatorTobaldini, Eleonora
dc.creatorMontano, Nicola
dc.creatorCatai, Aparecida M.
dc.date2014-05-20T15:31:41Z
dc.date2016-10-25T18:07:36Z
dc.date2014-05-20T15:31:41Z
dc.date2016-10-25T18:07:36Z
dc.date2012-06-01
dc.date.accessioned2017-04-06T00:23:26Z
dc.date.available2017-04-06T00:23:26Z
dc.identifierInternal and Emergency Medicine. New York: Springer, v. 7, n. 3, p. 229-235, 2012.
dc.identifier1828-0447
dc.identifierhttp://hdl.handle.net/11449/40748
dc.identifierhttp://acervodigital.unesp.br/handle/11449/40748
dc.identifier10.1007/s11739-011-0512-z
dc.identifierWOS:000305131100006
dc.identifierhttp://dx.doi.org/10.1007/s11739-011-0512-z
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/883495
dc.descriptionIncreasing age is associated with a reduction in overall heart rate variability as well as changes in complexity of physiologic dynamics. The aim of this study was to verify if the alterations in autonomic modulation of heart rate caused by the aging process could be detected by Shannon entropy (SE), conditional entropy (CE) and symbolic analysis (SA). Complexity analysis was carried out in 44 healthy subjects divided into two groups: old (n = 23, 63 +/- A 3 years) and young group (n = 21, 23 +/- A 2). It was analyzed SE, CE [complexity index (CI) and normalized CI (NCI)] and SA (0V, 1V, 2LV and 2ULV patterns) during short heart period series (200 cardiac beats) derived from ECG recordings during 15 min of rest in a supine position. The sequences characterized by three heart periods with no significant variations (0V), and that with two significant unlike variations (2ULV) reflect changes in sympathetic and vagal modulation, respectively. The unpaired t test (or Mann-Whitney rank sum test when appropriate) was used in the statistical analysis. In the aging process, the distributions of patterns (SE) remain similar to young subjects. However, the regularity is significantly different; the patterns are more repetitive in the old group (a decrease of CI and NCI). The amounts of pattern types are different: 0V is increased and 2LV and 2ULV are reduced in the old group. These differences indicate marked change of autonomic regulation. The CE and SA are feasible techniques to detect alteration in autonomic control of heart rate in the old group.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.languageeng
dc.publisherSpringer
dc.relationInternal and Emergency Medicine
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAging
dc.subjectHeart rate variability
dc.subjectNonlinear analysis
dc.subjectConditional entropy
dc.subjectSymbolic analysis
dc.titleAging reduces complexity of heart rate variability assessed by conditional entropy and symbolic analysis
dc.typeOtro


Este ítem pertenece a la siguiente institución