| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Moraes, M. S. | |
| dc.creator | Leite, SRA | |
| dc.date | 2014-05-20T15:29:21Z | |
| dc.date | 2016-10-25T18:04:36Z | |
| dc.date | 2014-05-20T15:29:21Z | |
| dc.date | 2016-10-25T18:04:36Z | |
| dc.date | 1994-11-01 | |
| dc.date.accessioned | 2017-04-06T00:11:35Z | |
| dc.date.available | 2017-04-06T00:11:35Z | |
| dc.identifier | Brazilian Journal of Medical and Biological Research. São Paulo: Associação Bras Divulg Cientifica, v. 27, n. 11, p. 2635-2638, 1994. | |
| dc.identifier | 0100-879X | |
| dc.identifier | http://hdl.handle.net/11449/38954 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/38954 | |
| dc.identifier | WOS:A1994PQ37600017 | |
| dc.identifier | http://www.scielo.br/scielo.php?script=sci_issues&pid=0100-879X&lng=en&nrm=iso | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/881960 | |
| dc.description | We report the in vitro inhibitory effect of very low concentrations of aluminum salts (IC50 = 4.1 X 10(-12)M) on bovine brain acetylcholinesterase (AChE). The enzymatic assays were performed using acetylcholine bromide in a buffered pH 7.4 solution at 37 degrees C. The relevant enzyme interacting species is the Al3+ ion, whose concentrations were fixed at pM levels by a citrate metal ion buffer system. The IC50 demonstrates that Al3+ is a potent inhibitor of AChE. | |
| dc.language | eng | |
| dc.publisher | Associação Brasileira de Divulgação Científica (ABRADIC) | |
| dc.relation | Brazilian Journal of Medical and Biological Research | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | ALUMINUM | |
| dc.subject | ACETYLCHOLINESTERASE | |
| dc.subject | BRAIN | |
| dc.title | INHIBITION OF BOVINE BRAIN ACETYLCHOLINESTERASE BY ALUMINUM | |
| dc.type | Otro | |
