Electrochemical oxidation and voltammetric determination of the antimalaria drug primaquine

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorArguelho, MLPM
dc.creatorZanoni, Maria Valnice Boldrin
dc.creatorStradiotto, Nelson Ramos
dc.date2014-05-20T15:29:10Z
dc.date2016-10-25T18:04:22Z
dc.date2014-05-20T15:29:10Z
dc.date2016-10-25T18:04:22Z
dc.date2005-01-01
dc.date.accessioned2017-04-06T00:10:39Z
dc.date.available2017-04-06T00:10:39Z
dc.identifierAnalytical Letters. Philadelphia: Taylor & Francis Inc., v. 38, n. 9, p. 1415-1425, 2005.
dc.identifier0003-2719
dc.identifierhttp://hdl.handle.net/11449/38803
dc.identifierhttp://acervodigital.unesp.br/handle/11449/38803
dc.identifier10.1081/AL-200062218
dc.identifierWOS:000230998200007
dc.identifier0000-0002-2296-1393
dc.identifierhttp://dx.doi.org/10.1081/AL-200062218
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/881842
dc.descriptionPrimaquine, an antimalarial drug, presents a well-defined oxidation peak around +0.6V vs SCE at a glassy carbon electrode that can be used for its determination. Calibration graphs were obtained for primaquine in B-R buffer pH 4.0 from 3.00 x 10(-5) mol L-1 to 1.00 x 10(-2) mol L-1 using linear-scan voltammetry and 3.00 x 10(-5) mol L-1 to 1.00 x 10(-2) mol L-1 using differential pulse or square-wave voltammetry. The correspondent detection limits was 9.4 mu g mL(-1); 4.2 and 1.8 mu g mL(-1), respectively. All the voltammetric methods were applied with success in direct determination of the primaquine in commercial tablets without separation or extraction procedures.
dc.languageeng
dc.publisherTaylor & Francis Inc
dc.relationAnalytical Letters
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectprimaquine
dc.subjectelectrooxidation
dc.subjectcyclic voltammetry
dc.subjectdifferential-pulse voltammetry
dc.subjectsquare-wave voltammetry
dc.titleElectrochemical oxidation and voltammetric determination of the antimalaria drug primaquine
dc.typeOtro


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