Anxiety levels and wild running susceptibility in rats: assessment with elevated plus maze test and predator odor exposure

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorde Paula, HMG
dc.creatorGouveia, A.
dc.creatorde Almeida, M. V.
dc.creatorHoshino, K.
dc.date2014-05-20T15:27:16Z
dc.date2016-10-25T18:02:03Z
dc.date2014-05-20T15:27:16Z
dc.date2016-10-25T18:02:03Z
dc.date2005-02-28
dc.date.accessioned2017-04-06T00:01:12Z
dc.date.available2017-04-06T00:01:12Z
dc.identifierBehavioural Processes. Amsterdam: Elsevier B.V., v. 68, n. 2, p. 135-144, 2005.
dc.identifier0376-6357
dc.identifierhttp://hdl.handle.net/11449/37283
dc.identifierhttp://acervodigital.unesp.br/handle/11449/37283
dc.identifier10.1016/j.beproc.2004.12.003
dc.identifierWOS:000227144300004
dc.identifierhttp://dx.doi.org/10.1016/j.beproc.2004.12.003
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/880629
dc.descriptionIt is reported in the literature that nearly 20% of rats are susceptible to displays of wild running (WR) behavior when submitted to high intensity acoustic stimulation. Some characteristics of WR suggest that it can be viewed as a panic-like reaction. This work aimed to test whether WR-sensitive rats show higher levels of anxiety in elevated-plus-maze (EPM) and predator-odor exposure paradigms in comparison with WR-resistant ones. Male adult Wistar rats were submitted to two trials of acoustic stimulation (104 dB, 60 s) in order to assess WR susceptibility. Seven WR-sensitive and 15 WR-resistant rats were evaluated by the EPM test. Other 13 WR-sensitive and 18 WR-resistant animals were submitted to the predator-odor exposure test which consisted of a 10 min-session of free exploration in a specific apparatus containing two odoriferous stimuli: cotton swab imbedded with snake cloacal gland secretion or with iguana feces (control). WR-sensitive rats presented a significantly higher closed-to open-ann-entry ratio in the EPM test. All rats responded with anxiety-like behaviors to the predator odor exposure, although the WR-sensitive ones showed a marked behavioral inhibition regardless of the odor condition. We conclude that WR-sensitive rats present elevated levels of anxiety manifested by means of passive behavioral strategies. (C) 2004 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationBehavioural Processes
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectanxiety
dc.subjectelevated-plus maze
dc.subjectpanic
dc.subjectpredator odor
dc.subjectrat
dc.subjectwild running
dc.titleAnxiety levels and wild running susceptibility in rats: assessment with elevated plus maze test and predator odor exposure
dc.typeOtro


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