dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorRosa, GJM
dc.creatorGianola, D.
dc.creatorPadovani, C. R.
dc.date2014-05-20T15:27:12Z
dc.date2016-10-25T18:01:58Z
dc.date2014-05-20T15:27:12Z
dc.date2016-10-25T18:01:58Z
dc.date2004-08-01
dc.date.accessioned2017-04-06T00:00:48Z
dc.date.available2017-04-06T00:00:48Z
dc.identifierJournal of Applied Statistics. Basingstoke: Carfax Publishing, v. 31, n. 7, p. 855-873, 2004.
dc.identifier0266-4763
dc.identifierhttp://hdl.handle.net/11449/37227
dc.identifierhttp://acervodigital.unesp.br/handle/11449/37227
dc.identifier10.1080/0266476042000214538
dc.identifierWOS:000223673500008
dc.identifierhttp://dx.doi.org/10.1080/0266476042000214538
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/880579
dc.descriptionLinear mixed effects models are frequently used to analyse longitudinal data, due to their flexibility in modelling the covariance structure between and within observations. Further, it is easy to deal with unbalanced data, either with respect to the number of observations per subject or per time period, and with varying time intervals between observations. In most applications of mixed models to biological sciences, a normal distribution is assumed both for the random effects and for the residuals. This, however, makes inferences vulnerable to the presence of outliers. Here, linear mixed models employing thick-tailed distributions for robust inferences in longitudinal data analysis are described. Specific distributions discussed include the Student-t, the slash and the contaminated normal. A Bayesian framework is adopted, and the Gibbs sampler and the Metropolis-Hastings algorithms are used to carry out the posterior analyses. An example with data on orthodontic distance growth in children is discussed to illustrate the methodology. Analyses based on either the Student-t distribution or on the usual Gaussian assumption are contrasted. The thick-tailed distributions provide an appealing robust alternative to the Gaussian process for modelling distributions of the random effects and of residuals in linear mixed models, and the MCMC implementation allows the computations to be performed in a flexible manner.
dc.languageeng
dc.publisherCarfax Publishing
dc.relationJournal of Applied Statistics
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectrobust-inference
dc.subjectlongitudinal study
dc.subjectmixed model
dc.subjectthick-tailed distribution
dc.subjectheteroscedasticity
dc.subjectBayesian inference
dc.titleBayesian longitudinal data analysis with mixed models and thick-tailed distributions using MCMC
dc.typeOtro


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