| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Queiroz, C. | |
| dc.creator | Barral-Netto, M. | |
| dc.creator | Bacchi, C. E. | |
| dc.date | 2014-05-20T15:26:49Z | |
| dc.date | 2016-10-25T18:01:27Z | |
| dc.date | 2014-05-20T15:26:49Z | |
| dc.date | 2016-10-25T18:01:27Z | |
| dc.date | 2001-01-01 | |
| dc.date.accessioned | 2017-04-05T23:58:46Z | |
| dc.date.available | 2017-04-05T23:58:46Z | |
| dc.identifier | Acta Cytologica. St Louis: Sci Printers & Publ Inc., v. 45, n. 1, p. 18-22, 2001. | |
| dc.identifier | 0001-5547 | |
| dc.identifier | http://hdl.handle.net/11449/36899 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/36899 | |
| dc.identifier | 10.1159/000327182 | |
| dc.identifier | WOS:000166823800004 | |
| dc.identifier | http://dx.doi.org/10.1159/000327182 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/880312 | |
| dc.description | OBJECTIVE: To analyze the role of immunochemistry in serous effusions.STUDY DESIGN: We analyzed cell blocks of 18 pleural and 18 peritoneal effusions diagnosed as malignant (18), benign (14) and suspicious (4). They were immunostained by the avidin-biotin complex method with a panel of four monoclonal antibodies-CEA, Ber-EP4, LeuM1 (CD15) and r53-and for lectins (Ulex europaeus) UEA-1, ConA and ConBr. RESULTS: Seventeen of the 18 cases of adenocarcinoma were positive for CEA (95%), 12 (66.6%)for Bev-EP4, 11 (61 %)for CD15 nild 11 (62 %)for p53. Twelve of the 18 (66.6%) were positive for UEA-1, CEA, Ber-EP4 and CD15. UEA-1 did not react with mesothelial cells. p53 Gave a positive reaction in only one case, reactive mesothelial cells. ConA and ConBr reacted indiscriminately with benign and malignant cells; thus, it was not useful in distinguishing between these cells.CONCLUSION: In this context no antibody used alone is reliable for corroborating a diagnosis, but the selective use of a small panel of three markers (CEA, Ber-EP4 and LeuM1) can be very useful in solving diagnostic difficulties in the cytodiagnosis of serous effusions. | |
| dc.language | eng | |
| dc.publisher | Sci Printers & Publ Inc | |
| dc.relation | Acta Cytologica | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | cells | |
| dc.subject | neoplasms | |
| dc.subject | immunocytochemistry | |
| dc.subject | serous effusions | |
| dc.title | Characterizing subpopulations of neoplastic cells in serous effusions - the role of immunocytochemistry | |
| dc.type | Otro | |
