| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Yada, M. M. | |
| dc.creator | Paula, Patricia Maria de | |
| dc.creator | Menani, José Vanderlei | |
| dc.creator | deLuca, L. A. | |
| dc.date | 2014-05-20T15:26:38Z | |
| dc.date | 2016-10-25T18:01:18Z | |
| dc.date | 2014-05-20T15:26:38Z | |
| dc.date | 2016-10-25T18:01:18Z | |
| dc.date | 1997-05-01 | |
| dc.date.accessioned | 2017-04-05T23:58:04Z | |
| dc.date.available | 2017-04-05T23:58:04Z | |
| dc.identifier | Pharmacology Biochemistry and Behavior. Oxford: Pergamon-Elsevier B.V., v. 57, n. 1-2, p. 137-143, 1997. | |
| dc.identifier | 0091-3057 | |
| dc.identifier | http://hdl.handle.net/11449/36776 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/36776 | |
| dc.identifier | 10.1016/S0091-3057(96)00317-6 | |
| dc.identifier | WOS:A1997XA08800019 | |
| dc.identifier | http://dx.doi.org/10.1016/S0091-3057(96)00317-6 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/880226 | |
| dc.description | In the present study, noradrenaline (NOR, alpha-non-specific adrenergic agonist), clonidine (CLO, alpha(2)), phenylephrine (PHE, alpha(1)) or isoproterenol (ISO, beta-agonist) was injected in the medial septal area (MSA) of water-deprived, sodium-deplete or food-deprived rats. NOR (80, 160 nmol) inhibited the intake of 3% NaCl, water deprivation-induced and meal-associated water intake. Food deprivation-induced food intake and 10% sucrose intake were not altered by NOR. CLO (10, 20, 30, 40 nmol) inhibited (80-100% inhibition compared to control during 60 min) the intake of 3% NaCl, water deprivation-induced and meal-associated water intake. CLO had a weaker inhibition on food and 10% sucrose intake (30-50% less than the control during 60 and 15 min, respectively). PHE (160 nmol) inhibited 3% NaCl intake and 10% sucrose intake (30% less than the control for 15-30 min). ISO (160 nmol) did not after water or 3% NaCl intake. NOR induced an increase, CLO and ISO induced a decrease, and PHE no alteration in mean arterial pressure. NOR did not alter water or 3% NaCl intake when injected unilaterally into the caudate nucleus. The results suggest that NOR injected in the MSA acts on alpha(2)-adrenergic receptors inducing a specific inhibition of 3% NaCl and water intake. (C) 1997 Elsevier B.V. | |
| dc.language | eng | |
| dc.publisher | Elsevier B.V. | |
| dc.relation | Pharmacology Biochemistry and Behavior | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | noradrenaline | |
| dc.subject | clonidine | |
| dc.subject | phenylephrine | |
| dc.subject | isoproterenol | |
| dc.subject | adrenergic agonists | |
| dc.subject | medial septal area | |
| dc.subject | water intake | |
| dc.subject | salt intake | |
| dc.subject | food intake | |
| dc.subject | blood pressure | |
| dc.title | Central alpha-adrenergic agonists and need-induced 3% NaCl and water intake | |
| dc.type | Otro | |
