Molecular fingerprinting methods for the discrimination between C-albicans and C-dubliniensis

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorNeppelenbroek, K. H.
dc.creatorCampanha, N. H.
dc.creatorSpolidório, Denise Madalena Palomari
dc.creatorSpolidório, Luis Carlos
dc.creatorSeo, R. S.
dc.creatorPavarina, Ana Claudia
dc.date2014-05-20T15:24:31Z
dc.date2016-10-25T17:58:45Z
dc.date2014-05-20T15:24:31Z
dc.date2016-10-25T17:58:45Z
dc.date2006-05-01
dc.date.accessioned2017-04-05T23:47:46Z
dc.date.available2017-04-05T23:47:46Z
dc.identifierOral Diseases. Oxford: Blackwell Publishing, v. 12, n. 3, p. 242-253, 2006.
dc.identifier1354-523X
dc.identifierhttp://hdl.handle.net/11449/35117
dc.identifierhttp://acervodigital.unesp.br/handle/11449/35117
dc.identifier10.1111/j.1601-0825.2005.01189.x
dc.identifierWOS:000237515000004
dc.identifierhttp://dx.doi.org/10.1111/j.1601-0825.2005.01189.x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/878911
dc.descriptionOpportunistic fungal pathogens are becoming increasingly important causes of both community-acquired and nosocomial infections. The most important fungal pathogens are yeast species belonging to the genus Candida. These species show differences in levels of resistance to antifungal agents and mortality. Consequently, it is important to correctly identify the causative organism to the species level. Identification of Candida dubliniensis in particular remains problematic because of the high degree of phenotypic similarity between this species and Candida albicans. However, as the differences between both are most pronounced at the genetic level, several studies have been conducted in order to provide a specific and rapid identification fingerprinting molecular test. In most candidal infectious, no single DNA fingerprinting technique has evolved as a dominant method, and each method has its advantages, disadvantages and limitations. Moreover, the current challenge of these techniques is to compile standardized patterns in a database for interlaboratory use and future reference. This review provides an overview of most common molecular fingerprinting techniques currently available for discrimination of C. albicans and C. dubliniensis.
dc.languageeng
dc.publisherBlackwell Publishing
dc.relationOral Diseases
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectcandidiasis
dc.subjectoral
dc.subjectCandida
dc.subjectCandida albicans
dc.subjectpathology
dc.subjectisolation & purification
dc.subjectCandida dubliniensis
dc.titleMolecular fingerprinting methods for the discrimination between C-albicans and C-dubliniensis
dc.typeOtro


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