Evaluation of quality of life related to i-131 therapy in patients with well-differentiated thyroid cancer and emphasis in salivary morbidity: a follow up study after treatment

dc.contributorHospital do Cancer de Barretos
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorCorrea, Lucelia Garcia
dc.creatorMoriguchi, Sônia Marta [UNESP]
dc.creatorBoldrini, Erica
dc.creatorCarvalho, Andre Lopes de
dc.creatorFregnani, José Humberto Tavares Guerreiro
dc.creatorRocha, Euclides Timóteo da
dc.date2016-04-01T18:43:07Z
dc.date2016-04-01T18:43:07Z
dc.date2014
dc.date.accessioned2023-09-12T09:10:16Z
dc.date.available2023-09-12T09:10:16Z
dc.identifierhttp://dx.doi.org/10.4236/abb.2014.55049
dc.identifierAdvances in Bioscience and Biotechnology, v. 5, n. 5, p. 409-417, 2014.
dc.identifier2156-8456
dc.identifierhttp://hdl.handle.net/11449/136888
dc.identifier10.4236/abb.2014.55049
dc.identifierISSN2156-8456-2014-05-05-409-417.pdf
dc.identifier9453740820853851
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8786130
dc.descriptionTo evaluate the impact of iodine-131 therapy received during childhood and adolescence and correlate it with the quality of life in these patients. Methods: We studied 19 patients diagnosed with cancer in childhood or adolescence who underwent thyroidectomy and supplemental therapy with I-131. We also recruited a control group of healthy subjects with the same demographic parameters. All patients were subjected to a scintigraphy examination of the salivary glands, and were also asked to complete a questionnaire in order to assess their overall quality of life. In addition, a more specific questionnaire for patients with head and neck cancer was also given to all study participants. Results: The quantitative and qualitative analyses of the salivary glands showed functional deficits with greater involvement of the parotid gland for volume, concentration and excretion. The right submandibular gland showed significant changes for volume in the patient group. The questionnaires made it possible to observe significant differences between the patient and control groups for symptoms such as thick saliva, dry mouth and speech problems. Conclusion: In spite of being very effective and widely used, iodine radionuclide therapy is correlated with a lower quality of life in young people.
dc.descriptionDepartment of Nuclear Medicine, Barretos Cancer Hospital, Barretos, Brazil
dc.descriptionUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Doenças Tropicais e Diagnóstico Por Imagem, Faculdade de Medicina de Botucatu, Botucatu, Distrito de Rubião Júnior, s/n, Rubião Júnior, CEP 18610250, SP, Brasil
dc.descriptionDepartment of Pediatrics, Barretos Cancer Hospital, Barretos, Brazil
dc.descriptionDepartment of Oncological Surgery, Barretos Cancer Hospital, Barretos, Brazil
dc.descriptionUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Doenças Tropicais e Diagnóstico Por Imagem, Faculdade de Medicina de Botucatu, Botucatu, Distrito de Rubião Júnior, s/n, Rubião Júnior, CEP 18610250, SP, Brasil
dc.format409-417
dc.languageeng
dc.relationAdvances in Bioscience and Biotechnology
dc.rightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectScintigraphy of the salivary glands
dc.subjectThyroid cancer
dc.subjectIodine radionuclide
dc.titleEvaluation of quality of life related to i-131 therapy in patients with well-differentiated thyroid cancer and emphasis in salivary morbidity: a follow up study after treatment
dc.typeArtigo


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