Optimization of extraction conditions and antioxidant activity of Solanum lycocarpum fruits

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade de São Paulo (USP)
dc.contributorCentro Universitário da Fundação Educacional de Barretos (UNIFEB)
dc.creatorMartins, Gilmarcio Zimmermann [UNESP]
dc.creatorSantos, Adriana Nogueira dos
dc.creatorVilela, Marcos Vinicius Ribeiro [UNESP]
dc.creatorFerreira, Mariana de Carvalho
dc.creatorOliveira, Wanderley Pereira de
dc.creatorMoreira, Raquel Regina Duarte [UNESP]
dc.date2016-01-28T16:56:46Z
dc.date2016-01-28T16:56:46Z
dc.date2013
dc.date.accessioned2023-09-12T08:17:19Z
dc.date.available2023-09-12T08:17:19Z
dc.identifierhttp://dx.doi.org/10.3923/jas.2013.147.153
dc.identifierJournal of Applied Sciences, v. 13, n. 1, p. 147-153, 2013.
dc.identifier1812-5654
dc.identifierhttp://hdl.handle.net/11449/133822
dc.identifier10.3923/jas.2013.147.153
dc.identifier5428026157324223
dc.identifier3976601131123566
dc.identifier7710344461864924
dc.identifier0000-0002-4253-0320
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8783074
dc.descriptionAntioxidants are substances that may protect cells from the damage caused by unstable molecules known as free radicals. The capacity of natural antioxidant from phytochemical has increase attention from researchers and public. However, the extraction process is affecting the activity and the bioavailability of bioactive compounds. The Solanum lycocarpum is a plant of the Brazilian “cerrado”, popularly used as a hypoglycemic, hypocholesterolemic and control of metabolic diseases. Its effects are attributed to the presence of several glycoalkaloids (solamargine, solasonina) and solasodine. Therefore, the purpose of this communication was, investigate the optimization of extraction condition and evaluation of antioxidant activity from fruits of Solanum lycocarpum. The extracts were obtained using different solvent systems, i.e., water, 50% ethanol, ethanol absolute and ethyl ether (1:10 and 1:20) and different extraction processes: maceration with constant agitation at room temperature, maceration with constant agitation and heating at 30°C and ultrasound. The extracts were characterized by the amount of material extracted (1, 6 and 24 h) and the action of antioxidant activity by DPPH method. The results showed that the polar solvent (50% ethanol) and extractive process maceration with agitation to ambient temperature showed higher contents of extractable of fruits of S. lycocarpum (3.4 g %) and also showed higher antioxidant activity (88.57±2.41% de inhibition). This action whether the presence of glycoalkaloids (solamargine, solasonine and solasodine) in fruits S. lycocarpum which are polar compounds and may explain this increased antioxidant action of this extract.
dc.descriptionUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Princípios Ativos Naturais e Toxicologia, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara Jaú Km 1, CEP 14801-902, SP, Brasil
dc.descriptionUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Princípios Ativos Naturais e Toxicologia, Faculdade de Ciências Farmacêuticas de Araraquara, Araraquara, Rodovia Araraquara Jaú Km 1, CEP 14801-902, SP, Brasil
dc.format147-153
dc.languageeng
dc.relationJournal of Applied Sciences
dc.relation0,101
dc.rightsAcesso restrito
dc.sourceCurrículo Lattes
dc.titleOptimization of extraction conditions and antioxidant activity of Solanum lycocarpum fruits
dc.typeArtigo


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