Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorPelizon, A. C.
dc.creatorKaneno, Ramon
dc.creatorSoares, AMVC
dc.creatorMeira, D. A.
dc.creatorSartori, A.
dc.date2014-05-20T15:23:09Z
dc.date2016-10-25T17:57:00Z
dc.date2014-05-20T15:23:09Z
dc.date2016-10-25T17:57:00Z
dc.date2005-01-01
dc.date.accessioned2017-04-05T23:40:24Z
dc.date.available2017-04-05T23:40:24Z
dc.identifierPhysiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.
dc.identifier0862-8408
dc.identifierhttp://hdl.handle.net/11449/33989
dc.identifierhttp://acervodigital.unesp.br/handle/11449/33989
dc.identifierWOS:000233101100012
dc.identifierhttp://www.biomed.cas.cz/physiolres/2005/issue5/pelizon.htm
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/877991
dc.descriptionIn this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.
dc.languageeng
dc.publisherAcad Sciences Czech Republic, Inst Physiology
dc.relationPhysiological Research
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectbeta-glucan
dc.subjectIL-12
dc.subjectTNF-alpha
dc.subjectNK activity
dc.subjectfungicidal activity
dc.titleImmunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
dc.typeOtro


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