Healing at mandibular block-grafted sites: an experimental study in dogs

dc.contributorARDEC
dc.contributorUniversidade de Hong Kong
dc.contributorUniversidade de Zurich
dc.contributorUniversidade de Medicina Science
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorDe Santis, Enzo
dc.creatorLang, Niklaus P.
dc.creatorFavero, Giovanni
dc.creatorBeolchini, Marco
dc.creatorMorelli, Fabrizio
dc.creatorBotticelli, Daniele [UNESP]
dc.date2015-10-22T06:46:11Z
dc.date2015-10-22T06:46:11Z
dc.date2015-05-01
dc.date.accessioned2023-09-12T07:02:32Z
dc.date.available2023-09-12T07:02:32Z
dc.identifierhttp://onlinelibrary.wiley.com/doi/10.1111/clr.12434/full
dc.identifierClinical Oral Implants Research. Hoboken: Wiley-blackwell, v. 26, n. 5, p. 516-522, 2015.
dc.identifier0905-7161
dc.identifierhttp://hdl.handle.net/11449/129766
dc.identifier10.1111/clr.12434
dc.identifierWOS:000352562200005
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8779095
dc.descriptionAimThe aim of this study was to evaluate the healing of autologous bone block grafts or deproteinized bovine bone mineral (DBBM) block grafts applied concomitantly with collagen membranes for horizontal alveolar ridge augmentation.Material and methodsIn six Labrador dogs, molars were extracted bilaterally, the buccal bony wall was removed, and a buccal box-shaped defect created. After 3months, a bony block graft was harvested from the right ascending ramus of the mandible and reduced to a standardized size. A DBBM block was tailored to similar dimensions. The two blocks were secured with screws onto the buccal wall of the defects in the right and left sides of the mandible, respectively. Resorbable membranes were applied at both sides, and the flaps sutured. After 3months, one implant was installed in each side of the mandible, in the interface between grafts and parent bone. After 3months, biopsies were harvested and ground sections prepared to reveal a 6-month healing period of the grafts.Results776.2% and 5.9 +/- 7.5% of vital mineralized bone were found at the autologous bone and DBBM block graft sites, respectively. Moreover, at the DBBM site, 63 +/- 11.7% of connective tissue and 31 +/- 15.5% of DBBM occupied the area analyzed. Only 0.2 +/- 0.4% of DBBM was found in contact with newly formed bone. The horizontal loss was in a mean range of 0.9-1.8mm, and 0.3-0.8mm, at the autologous bone and DBBM block graft sites, respectively.ConclusionsAutologous bone grafts were vital and integrated to the parent bone after 6months of healing. In contrast, DBBM grafts were embedded into connective tissue, and only a limited amount of bone was found inside the scaffold of the biomaterial.
dc.descriptionSweden &Martina SRL, Due Carrare, Padova, Italy
dc.descriptionARDEC, Ariminum Odontologica SRL, Rimini, Italy
dc.descriptionClinical Research Foundation (CRF) for the Promotion of Oral Health, Brienz, Switzerland
dc.descriptionARDEC, Ariminum Odontol, Rimini, Italy
dc.descriptionUniv Hong Kong, Prince Philip Dent Hosp, Hong Kong, Hong Kong, Peoples R China
dc.descriptionUniv Zurich, Zurich, Switzerland
dc.descriptionUniv Med Sci, Fac Dent, Havana, Cuba
dc.descriptionUNESP Univ Estadual Paulista, Fac Dent Aracatuba, Sao Paulo, Brazil
dc.descriptionUNESP Universidade Estadual Paulista, Faculdade de Odontologia Araçatuba, Sao Paulo, Brazil
dc.format516-522
dc.languageeng
dc.publisherWiley-Blackwell
dc.relationClinical Oral Implants Research
dc.relation4.305
dc.relation2,462
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectAnimal study
dc.subjectBone defects
dc.subjectBone graft
dc.subjectBone healing
dc.subjectBone regeneration
dc.subjectDeproteinized bovine bone mineral
dc.subjectHistology
dc.titleHealing at mandibular block-grafted sites: an experimental study in dogs
dc.typeArtigo


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