Neuromuscular effects of venoms and crotoxin-like proteins from Crotalus durissus ruruima and Crotalus durissus cumanensis

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade Estadual de Campinas (UNICAMP)
dc.creatorGarrido Cavalcante, Walter Luis [UNESP]
dc.creatorPonce-Soto, Luis Alberto
dc.creatorMarangoni, Sergio
dc.creatorGallacci, Marcia [UNESP]
dc.date2015-10-21T21:20:50Z
dc.date2015-10-21T21:20:50Z
dc.date2015-03-01
dc.date.accessioned2023-09-12T06:56:50Z
dc.date.available2023-09-12T06:56:50Z
dc.identifierhttp://www.sciencedirect.com/science/article/pii/S0041010115000094
dc.identifierToxicon. Oxford: Pergamon-elsevier Science Ltd, v. 96, p. 46-49, 2015.
dc.identifier0041-0101
dc.identifierhttp://hdl.handle.net/11449/129552
dc.identifier10.1016/j.toxicon.2015.01.006
dc.identifierWOS:000350922700005
dc.identifier9353490382598257
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8778890
dc.descriptionA myographic study was performed to compare the neuromuscular effects of venoms and crotoxin-like proteins from Crotalus durissus ruruima and Crotalus durissus cumanensis in mice phrenic-diaphragm preparation. It was concluded that both venoms present neurotoxic activity as a consequence of their crotoxin content. Furthermore, crotoxin from C.d. cumanensis is more potent than that from C.d. ruruima venom. At the concentration range in which both venoms express neurotoxic activity, only C.d. cumanensis venom also manifest a direct myotoxic effect that probably involves the synergic participation of other components than crotoxin. (C) 2015 Elsevier Ltd. All rights reserved.
dc.descriptionSao Paulo State University (UNESP), Bioscience Institute of Botucatu, Botucatu, SP, Brazil
dc.descriptionUniversity of Campinas (UNICAMP), Biological Institute, Campinas, SP, Brazil
dc.descriptionSao Paulo State University (UNESP), Bioscience Institute of Botucatu, Botucatu, SP, Brazil
dc.format46-49
dc.languageeng
dc.publisherElsevier B.V.
dc.relationToxicon
dc.relation2.352
dc.relation0,692
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectSnake venom
dc.subjectNeurotoxin
dc.subjectNeuromuscular transmission
dc.subjectCrotalus subspecies
dc.titleNeuromuscular effects of venoms and crotoxin-like proteins from Crotalus durissus ruruima and Crotalus durissus cumanensis
dc.typeArtigo


Este ítem pertenece a la siguiente institución