Mathematical modeling of a continuous alcoholic fermentation process in a two-stage tower reactor cascade with flocculating yeast recycle

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade de São Paulo (USP)
dc.creatorOliveira, Samuel Conceição de [UNESP]
dc.creatorCastro, Heizir Ferreira de
dc.creatorVisconti, Alexandre Eliseu Stourdze
dc.creatorGiudici, Reinaldo
dc.date2015-10-21T20:19:13Z
dc.date2015-10-21T20:19:13Z
dc.date2015-03-01
dc.date.accessioned2023-09-12T06:48:06Z
dc.date.available2023-09-12T06:48:06Z
dc.identifierhttp://link.springer.com/article/10.1007%2Fs00449-014-1286-2
dc.identifierBioprocess And Biosystems Engineering. New York: Springer, v. 38, n. 3, p. 469-479, 2015.
dc.identifier1615-7591
dc.identifierhttp://hdl.handle.net/11449/129075
dc.identifier10.1007/s00449-014-1286-2
dc.identifierWOS:000350350000007
dc.identifier2041303049625571
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8778415
dc.descriptionExperiments of continuous alcoholic fermentation of sugarcane juice with flocculating yeast recycle were conducted in a system of two 0.22-L tower bioreactors in series, operated at a range of dilution rates (D (1) = D (2) = 0.27-0.95 h(-1)), constant recycle ratio (alpha = F (R) /F = 4.0) and a sugar concentration in the feed stream (S (0)) around 150 g/L. The data obtained in these experimental conditions were used to adjust the parameters of a mathematical model previously developed for the single-stage process. This model considers each of the tower bioreactors as a perfectly mixed continuous reactor and the kinetics of cell growth and product formation takes into account the limitation by substrate and the inhibition by ethanol and biomass, as well as the substrate consumption for cellular maintenance. The model predictions agreed satisfactorily with the measurements taken in both stages of the cascade. The major differences with respect to the kinetic parameters previously estimated for a single-stage system were observed for the maximum specific growth rate, for the inhibition constants of cell growth and for the specific rate of substrate consumption for cell maintenance. Mathematical models were validated and used to simulate alternative operating conditions as well as to analyze the performance of the two-stage process against that of the single-stage process.
dc.descriptionUniversidade de São Paulo, Departamento de Engenharia Química, Escola de Engenharia de Lorena
dc.descriptionUniversidade de São Paulo, Departamento de Biotecnologia, Escola de Engenharia de Lorena
dc.descriptionUniversidade de São Paulo, Departamento de Engenharia Química, Escola Politécnica
dc.descriptionUniversidade Estadual Paulista, Departamento de Bioprocessos e Biotecnologia, Faculdade de Ciências Farmacêuticas de Araraquara
dc.format469-479
dc.languageeng
dc.publisherSpringer
dc.relationBioprocess And Biosystems Engineering
dc.relation2.139
dc.relation0,640
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectMathematical modeling
dc.subjectContinuous ethanol fermentation
dc.subjectFlocculating yeast
dc.subjectTower reactor cascade
dc.titleMathematical modeling of a continuous alcoholic fermentation process in a two-stage tower reactor cascade with flocculating yeast recycle
dc.typeArtigo


Este ítem pertenece a la siguiente institución