Influence of nicotine and cotinine impregnation on the first step of periodontal regeneration: clot stabilization

dc.contributorUniversidade Estadual de Ponta Grossa (UEPG)
dc.contributorUniversidade Federal de Pelotas (UFPEL)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade Ceuma
dc.contributorUniversidade de Cuiabá (UNIC)
dc.creatorPinto, Shelon Cristina Souza
dc.creatorLeite, Fabio Renato Manzolli
dc.creatorFontanari, Lucas Amaral
dc.creatorCavassim, Rodrigo
dc.creatorLeite, Amauri Antiqueira
dc.creatorBandéca, Mateus Coelho
dc.creatorBorges, Alvaro Henrique
dc.creatorSampaio, Jose Eduardo Cezar [UNESP]
dc.date2015-08-06T16:12:53Z
dc.date2015-08-06T16:12:53Z
dc.date2013
dc.date.accessioned2023-09-12T05:45:51Z
dc.date.available2023-09-12T05:45:51Z
dc.identifierhttp://www.jaypeejournals.com/eJournals/Abstract.aspx?id=5824&AID=24&num=9
dc.identifierThe Journal of Contemporary Dental Practice, v. 14, n. 6, p. 1044-1048, 2013.
dc.identifier1526-3711
dc.identifierhttp://hdl.handle.net/11449/125704
dc.identifier10.5005/jp-journals-10024-1448
dc.identifier5001834460012280
dc.identifier0652077402764417
dc.identifier7713504467337236
dc.identifier9531839078426485
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8775103
dc.descriptionThis study analyzes the clot stabilization on root surfaces of teeth impregnated with cotinine and nicotine and the influence of the scaling in the adhesion of blood components, observing the influence of new exposition to nicotine and/or cotinine after scaling. Fifteen human teeth extracted due to periodontal disease of non-smokers patients were selected and manually scaled. Four dentin blocks were obtained from each tooth (n = 60). Samples received blood application or reimpregnation with nicotine and/or cotinine, depending on the groups. Group 1: PBS immersion + root scaling + blood; group 2: nicotine + root scaling + blood; group 3: nicotine + root scaling + nicotine reapplication + blood; group 4: cotinine + root scaling + blood; group 5: cotinine + root scaling + cotinine reapplication+ blood; group 6: nicotine and cotinine + root scaling + nicotine and cotinine + blood. Samples were kept in 2 ml of each substance for 24 hours. Each group received a blood drop and was analyzed by SEM. The higher amount of blood components was present in teeth exposed to cotinine and the groups submitted to scaling and blood application in comparison with groups that received reapplication of toxic substances after scaling. The greater toxic effect on root dentin surface was after the exposure to nicotine and cotinine. Results suggest that periodontal healing may be delayed in smokers due to the direct inhibition of clot stabilization on the root surface when nicotine and cotinine are present concomitantly.
dc.descriptionUniversidade Estadual de Ponta Grossa, Departamento de Odontologia
dc.descriptionUniversidade Federal de Pelotas, Departamento de Semiologia e Clínicas
dc.descriptionUniversidade Ceuma, Departamento de Pós-graduação em Odontologia
dc.descriptionUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Diagnóstico e Cirurgia, Faculdade de Odontologia de Araraquara
dc.descriptionUniversidade Estadual Paulista Júlio de Mesquita Filho, Departamento de Análises Clínicas, Faculdade de Ciências Farmacêuticas de Araraquara
dc.format1044-1048
dc.languageeng
dc.relationThe Journal of Contemporary Dental Practice
dc.relation0,263
dc.rightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectClot stabilization
dc.subjectPeriodontal regeneration
dc.subjectNicotine
dc.subjectCotinine
dc.titleInfluence of nicotine and cotinine impregnation on the first step of periodontal regeneration: clot stabilization
dc.typeArtigo


Este ítem pertenece a la siguiente institución