Kinetics of rabies antibodies as a strategy for canine active immunization

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorCtr Control Zoonosis Sao Paulo City
dc.creatorBabboni, Selene Daniela [UNESP]
dc.creatorCosta, Heni Falcao da [UNESP]
dc.creatorAlves Martorelli, Luzia de Fatima
dc.creatorArruda Geraldes Kataoka, Ana Paula de
dc.creatorVictória, Cassiano [UNESP]
dc.creatorPadovani, Carlos Roberto [UNESP]
dc.creatorModolo, José Rafael [UNESP]
dc.date2015-03-18T15:55:50Z
dc.date2015-03-18T15:55:50Z
dc.date2014-08-26
dc.date.accessioned2023-09-12T03:10:09Z
dc.date.available2023-09-12T03:10:09Z
dc.identifierhttp://dx.doi.org/10.1186/1678-9199-20-37
dc.identifierJournal Of Venomous Animals And Toxins Including Tropical Diseases. London: Biomed Central Ltd, v. 20, 4 p., 2014.
dc.identifier1678-9199
dc.identifierhttp://hdl.handle.net/11449/117321
dc.identifier10.1186/1678-9199-20-37
dc.identifierWOS:000342099600001
dc.identifierWOS000342099600001.pdf
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8766806
dc.descriptionBackground: Rabies, a zoonosis found throughout the globe, is caused by a virus of the Lyssavirus genus. The disease is transmitted to humans through the inoculation of the virus present in the saliva of infected mammals. Since its prognosis is usually fatal for humans, nationwide public campaigns to vaccinate dogs and cats against rabies aim to break the epidemiological link between the virus and its reservoirs in Brazil.Findings: During 12 months we evaluated the active immunity of dogs first vaccinated (booster shot at 30 days after first vaccination) against rabies using the Fuenzalida-Palacios modified vaccine in the urban area of Botucatu city, Sao Pauto state, Brazil. Of the analyzed dogs, 54.7% maintained protective titers (>= 0.5 IU/mL) for 360 days after the first vaccination whereas 51.5% during all the study period.Conclusions: The present results suggest a new vaccination schedule for dogs that have never been vaccinated. In addition to the first dose of vaccine, two others are recommended: the second at 30 days after the first and the third dose at 180 days after the first for the maintenance of protective titers during 12 months.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionSao Paulo State Univ, Univ Estadual Paulista, UNESP, Sch Vet Med & Anim Husb,Dept Vet Hyg & Publ Hlth, Botucatu, SP, Brazil
dc.descriptionSao Paulo State Univ, Univ Estadual Paulista, UNESP, Sch Vet Med,Dept Anim Hlth & Prod, Aracatuba, SP, Brazil
dc.descriptionCtr Control Zoonosis Sao Paulo City, Lab Zoonoses & Vector Borne Dis, Sao Paulo, Brazil
dc.descriptionSao Paulo State Univ, Univ Estadual Paulista, UNESP, Dept Biostat,Botucatu Biosci Inst, Botucatu, SP, Brazil
dc.descriptionSao Paulo State Univ, Univ Estadual Paulista, UNESP, Sch Vet Med & Anim Husb,Dept Vet Hyg & Publ Hlth, Botucatu, SP, Brazil
dc.descriptionSao Paulo State Univ, Univ Estadual Paulista, UNESP, Sch Vet Med,Dept Anim Hlth & Prod, Aracatuba, SP, Brazil
dc.descriptionSao Paulo State Univ, Univ Estadual Paulista, UNESP, Dept Biostat,Botucatu Biosci Inst, Botucatu, SP, Brazil
dc.descriptionFAPESP: 09-09098-8
dc.format4
dc.languageeng
dc.publisherBiomed Central Ltd
dc.relationJournal Of Venomous Animals And Toxins Including Tropical Diseases
dc.relation1.782
dc.relation0,573
dc.rightsAcesso aberto
dc.sourceWeb of Science
dc.subjectRabies
dc.subjectDogs
dc.subjectVaccination
dc.subjectRevaccination
dc.subjectAnnual vaccination campaign
dc.subjectFuenzalida-Palacios
dc.titleKinetics of rabies antibodies as a strategy for canine active immunization
dc.typeArtigo


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