The phylogeny and ontogeny of autonomic control of the heart and cardiorespiratory interactions in vertebrates

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniv Birmingham
dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.contributorNatl Inst Sci & Technol Comparat Physiol
dc.contributorAarhus Univ
dc.contributorUniv N Texas
dc.creatorTaylor, Edwin W. [UNESP]
dc.creatorLeite, Cleo A. C.
dc.creatorSartori, Marina R.
dc.creatorWang, Tobias
dc.creatorAbe, Augusto S.
dc.creatorCrossley, Dane A.
dc.date2014-12-03T13:11:05Z
dc.date2014-12-03T13:11:05Z
dc.date2014-03-01
dc.date.accessioned2023-09-09T10:05:23Z
dc.date.available2023-09-09T10:05:23Z
dc.identifierhttp://dx.doi.org/10.1242/jeb.086199
dc.identifierJournal Of Experimental Biology. Cambridge: Company Of Biologists Ltd, v. 217, n. 5, p. 690-703, 2014.
dc.identifier0022-0949
dc.identifierhttp://hdl.handle.net/11449/112827
dc.identifier10.1242/jeb.086199
dc.identifierWOS:000332041600015
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8762446
dc.descriptionHeart rate in vertebrates is controlled by activity in the autonomic nervous system. In spontaneously active or experimentally prepared animals, inhibitory parasympathetic control is predominant and is responsible for instantaneous changes in heart rate, such as occur at the first air breath following a period of apnoea in discontinuous breathers like inactive reptiles or species that surface to air breathe after a period of submersion. Parasympathetic control, exerted via fast-conducting, myelinated efferent fibres in the vagus nerve, is also responsible for beat-to-beat changes in heart rate such as the high frequency components observed in spectral analysis of heart rate variability. These include respiratory modulation of the heartbeat that can generate cardiorespiratory synchrony in fish and respiratory sinus arrhythmia in mammals. Both may increase the effectiveness of respiratory gas exchange. Although the central interactions generating respiratory modulation of the heartbeat seem to be highly conserved through vertebrate phylogeny, they are different in kind and location, and in most species are as yet little understood. The heart in vertebrate embryos possesses both muscarinic cholinergic and beta-adrenergic receptors very early in development. Adrenergic control by circulating catecholamines seems important throughout development. However, innervation of the cardiac receptors is delayed and first evidence of a functional cholinergic tonus on the heart, exerted via the vagus nerve, is often seen shortly before or immediately after hatching or birth, suggesting that it may be coordinated with the onset of central respiratory rhythmicity and subsequent breathing.
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionNational Science Foundation
dc.descriptionUniv Estadual Paulista, Dept Zool, Inst Biociencias, BR-13506900 Sao Paulo, Brazil
dc.descriptionUniv Birmingham, Sch Biosci, Birmingham B15 2TT, W Midlands, England
dc.descriptionUniv Fed Sao Paulo, Dept Ciencias Biol, BR-04021001 Sao Paulo, Brazil
dc.descriptionNatl Inst Sci & Technol Comparat Physiol, Sao Carlos, SP, Brazil
dc.descriptionAarhus Univ, Dept Biosci, DK-8000 Aarhus, Denmark
dc.descriptionUniv N Texas, Dept Biol Sci, Dev Integrat Biol Cluster, Denton, TX 76203 USA
dc.descriptionUniv Estadual Paulista, Dept Zool, Inst Biociencias, BR-13506900 Sao Paulo, Brazil
dc.descriptionCNPq: INCT 573921/2008-3
dc.descriptionFAPESP: 08/57712-4
dc.descriptionFAPESP: 10/51995-4
dc.descriptionFAPESP: 08/00107-1
dc.descriptionFAPESP: 12/06938-8
dc.descriptionFAPESP: 12/16537-0
dc.descriptionNational Science FoundationIOS-0845741
dc.format690-703
dc.languageeng
dc.publisherCompany of Biologists Ltd
dc.relationJournal of Experimental Biology
dc.relation3.179
dc.relation1,611
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectAutonomic nervous system
dc.subjectParasympathetic tonus
dc.subjectCardiorespiratory interaction
dc.subjectHeart rate variability
dc.subjectRespiratory sinus arrhythmia
dc.subjectOntogeny
dc.subjectVertebrate
dc.titleThe phylogeny and ontogeny of autonomic control of the heart and cardiorespiratory interactions in vertebrates
dc.typeArtigo


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