MALDI Imaging Analysis of Neuropeptides in the Africanized Honeybee (Apis mellifera) Brain: Effect of Ontogeny

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorPratavieira, Marcel [UNESP]
dc.creatorSilva Menegasso, Anally Ribeiro da [UNESP]
dc.creatorCaviquioli Garcia, Ana Maria [UNESP]
dc.creatorSantos, Diego Simoes dos [UNESP]
dc.creatorGomes, Paulo Cesar [UNESP]
dc.creatorMalaspina, Osmar [UNESP]
dc.creatorPalma, Mario Sergio [UNESP]
dc.date2014-12-03T13:11:00Z
dc.date2014-12-03T13:11:00Z
dc.date2014-06-01
dc.date.accessioned2023-09-09T10:03:39Z
dc.date.available2023-09-09T10:03:39Z
dc.identifierhttp://dx.doi.org/10.1021/pr500224b
dc.identifierJournal Of Proteome Research. Washington: Amer Chemical Soc, v. 13, n. 6, p. 3054-3064, 2014.
dc.identifier1535-3893
dc.identifierhttp://hdl.handle.net/11449/112720
dc.identifier10.1021/pr500224b
dc.identifierWOS:000337074500030
dc.identifier7538556085505819
dc.identifier2901888624506535
dc.identifier3637285622123132
dc.identifier0000-0003-2440-8097
dc.identifier0000-0002-1650-257X
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8762341
dc.descriptionThe occurrence and spatial distribution of the neuropeptides AmTRP-5 and AST-1 in the honeybee brain were monitored via MALDI spectral imaging according to the ontogeny of Africanized Apis mellifera. The levels of these peptides increased in the brains of 0-15 day old honeybees, and this increase was accompanied by an increase in the number of in-hive activities performed by the nurse bees, followed by a decrease in the period from 15 to 25 days of age, in which the workers began to perform activities outside the nest (guarding and foraging). The results obtained in the present investigation suggest that AmTRP-5 acts in the upper region of both pedunculi of young workers, possibly regulating the cell cleaning and brood capping activities. Meanwhile, the localized occurrence of AmTRP-5 and AST-1 in the antennal lobes, subesophageal ganglion, upper region of the medulla, both lobula, and alpha- and beta-lobes of both brain hemispheres in 20 to 25 day old workers suggest that the action of both neuropeptides in these regions may be related to their localized actions in these regions, regulating foraging and guarding activities. Thus, these neuropeptides appear to have some functions in the honeybee brain that are specifically related to the age-related division of labor.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionUniv Sao Paulo State UNESP, Dept Biol, Ctr Study Social Insects, Inst Biosci, BR-13506900 Rio Claro, SP, Brazil
dc.descriptionUniv Sao Paulo State UNESP, Dept Biol, Ctr Study Social Insects, Inst Biosci, BR-13506900 Rio Claro, SP, Brazil
dc.descriptionFAPESP: 11/51684-1
dc.format3054-3064
dc.languageeng
dc.publisherAmer Chemical Soc
dc.relationJournal of Proteome Research
dc.relation3.950
dc.relation1,818
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectMALDI imaging
dc.subjectmass spectrometry
dc.subjecthoneybee brain
dc.subjectneuropeptides
dc.subjectontogeny
dc.subjectproteomics
dc.titleMALDI Imaging Analysis of Neuropeptides in the Africanized Honeybee (Apis mellifera) Brain: Effect of Ontogeny
dc.typeArtigo


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