Effect of low-fluoride toothpastes combined with hexametaphosphate on in vitro enamel demineralization

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorCamara, Danielle Mendes da [UNESP]
dc.creatorMiyasaki, Marcela Lumi [UNESP]
dc.creatorDanelon, Marcelle [UNESP]
dc.creatorSassaki, Kikue Takebayashi [UNESP]
dc.creatorDelbem, Alberto Carlos Botazzo [UNESP]
dc.date2014-12-03T13:10:44Z
dc.date2014-12-03T13:10:44Z
dc.date2014-03-01
dc.date.accessioned2023-09-09T09:59:43Z
dc.date.available2023-09-09T09:59:43Z
dc.identifierhttp://dx.doi.org/10.1016/j.jdent.2013.12.002
dc.identifierJournal Of Dentistry. Oxford: Elsevier Sci Ltd, v. 42, n. 3, p. 256-262, 2014.
dc.identifier0300-5712
dc.identifierhttp://hdl.handle.net/11449/112467
dc.identifier10.1016/j.jdent.2013.12.002
dc.identifierWOS:000332414000005
dc.identifier7239471016654133
dc.identifier0000-0002-8159-4853
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8762095
dc.descriptionObjectives: The aim of this study was to evaluate the anticaries effect of low-fluoride toothpastes combined with hexametaphosphate (HMP) on enamel demineralization.Methods: Bovine enamel blocks were subjected to pH cycling and treatment with toothpaste's slurries (15 groups; 2x/day). Toothpaste mixtures contained the following: no fluoride (F) plus HMP (from 0 to 3.0%); 250 ppm F plus HMP (from 0 to 3.0%); 500 ppm F; 1100 ppm F; and a commercial toothpaste (1100 ppm F). After pH cycling, surface and cross-sectional hardness, as well as F present in the enamel were determined. The demineralization depth was analyzed using polarized light microscopy. The variables were subjected to 1-way ANOVA, followed by Student-Newman-Keuls' test (p < 0.05).Results: In the absence of fluoride, 0.5% HMP promoted the lowest mineral loss and its effect was similar to that of a 250 ppm F toothpaste (p > 0.05). The combination of 0.5% HMP and 250 ppm F resulted in lower mineral loss (p < 0.05) and similar lesion depth when compared to the 1100 ppm F toothpaste (p > 0.05).Conclusion: To conclude, the combination of 0.5% HMP and 250 ppm fluoride in a toothpaste has a similar inhibitory effect on enamel demineralization in vitro when compared to a toothpaste containing 1100 ppm F.Clinical significance: The anticaries effect of toothpaste containing 250 ppm F combined with 0.5% HMP was similar to that of a 1100 ppm F toothpaste, despite the 4-fold difference in F concentration. Although such effects still need to be demonstrated in clinical studies, it may be a viable alternative for preschool children. (C) 2013 Elsevier Ltd. All rights reserved.
dc.descriptionUniv Estadual Paulista, UNESP, Aracatuba Dent Sch, Dept Pediat Dent & Publ Hlth, BR-16015050 Sao Paulo, Brazil
dc.descriptionUniv Estadual Paulista, UNESP, Aracatuba Dent Sch, Dept Basic Sci, BR-16015050 Sao Paulo, Brazil
dc.descriptionUniv Estadual Paulista, UNESP, Aracatuba Dent Sch, Dept Pediat Dent & Publ Hlth, BR-16015050 Sao Paulo, Brazil
dc.descriptionUniv Estadual Paulista, UNESP, Aracatuba Dent Sch, Dept Basic Sci, BR-16015050 Sao Paulo, Brazil
dc.format256-262
dc.languageeng
dc.publisherElsevier B.V.
dc.relationJournal of Dentistry
dc.relation3.770
dc.relation1,919
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectDemineralization
dc.subjectDental enamel
dc.subjectPhosphates
dc.subjectFluoride
dc.subjectToothpaste
dc.subjectpH cycling
dc.titleEffect of low-fluoride toothpastes combined with hexametaphosphate on in vitro enamel demineralization
dc.typeArtigo


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