dc.contributorUniversidade de São Paulo (USP)
dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
dc.creatorRosario, M. F.
dc.creatorGazaffi, R.
dc.creatorMoura, Ana Silvia Alves Meira Tavares [UNESP]
dc.creatorLedur, M. C.
dc.creatorCoutinho, L. L.
dc.creatorGarcia, A. A. F.
dc.date2014-12-03T13:10:39Z
dc.date2014-12-03T13:10:39Z
dc.date2014-02-01
dc.date.accessioned2023-09-09T09:57:57Z
dc.date.available2023-09-09T09:57:57Z
dc.identifierhttp://dx.doi.org/10.1007/s13353-013-0185-6
dc.identifierJournal Of Applied Genetics. Heidelberg: Springer Heidelberg, v. 55, n. 1, p. 97-103, 2014.
dc.identifier1234-1983
dc.identifierhttp://hdl.handle.net/11449/112358
dc.identifier10.1007/s13353-013-0185-6
dc.identifierWOS:000331197900009
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8761986
dc.descriptionInterval mapping (IM) implemented in QTL Express or GridQTL is widely used, but presents some limitations, such as restriction to a fixed model, risk of mapping two QTL when there may be only one and no discrimination of two or more QTL using both cofactors located on the same and other chromosomes. These limitations were overcome with composite interval mapping (CIM). We reported QTL associated with performance and carcass traits on chicken chromosomes 1, 3, and 4 through implementation of CIM and analysis of phenotypic data using mixed models. Thirty-four microsatellite markers were used to genotype 360 F-2 chickens from crosses between males from a layer line and females from a broiler line. Sixteen QTL were mapped using CIM and 14 QTL with IM. Furthermore, of those 30 QTL, six were mapped only when CIM was used: for body weight at 35 days (first and third peaks on GGA4), body weight at 41 days (GGA1B and second peak on GGA4), and weights of back and legs (both on GGA4). Three new regions had evidence for QTL presence: one on GGA1B associated with feed intake 35-41 d at 404 cM (LEI0107-ADL0183) and two on GGA4 associated with weight of back at 163 cM (LEI0076-MCW0240) and weight gain 35-41 d, feed efficiency 35-41 d and weight of legs at 241 cM (LEI0085-MCW0174). We dissected one more linked QTL on GGA4, where three QTL for BW35 and two QTL for BW41 were mapped. Therefore, these new regions mapped here need further investigations using high-density SNP to confirm these QTL and identify candidate genes associated with those traits.
dc.descriptionEmbrapa/PRODETAB
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionUniv Sao Paulo, Escola Super Agr Luiz de Queiroz, Dept Zootecnia, BR-13418900 Sao Paulo, Brazil
dc.descriptionUniv Fed Sao Paulo, Sao Paulo, Brazil
dc.descriptionUniv Estadual Paulista, Fac Med Vet & Zootecnia, Dept Prod Anim, BR-18618000 Botucatu, SP, Brazil
dc.descriptionEmbrapa Suinos & Aves, BR-89700000 Concordia, SC, Brazil
dc.descriptionUniv Estadual Paulista, Fac Med Vet & Zootecnia, Dept Prod Anim, BR-18618000 Botucatu, SP, Brazil
dc.descriptionFAPESP: 04/02080-2
dc.descriptionFAPESP: 10/50019-1
dc.descriptionFAPESP: 12/13272-6
dc.descriptionCNPq: 152500-2007/3
dc.format97-103
dc.languageeng
dc.publisherSpringer
dc.relationJournal of Applied Genetics
dc.relation1.756
dc.relation0,704
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectGenetic architecture
dc.subjectMarker assisted selection
dc.subjectMolecular markers
dc.subjectPoultry
dc.titleComposite interval mapping and mixed models reveal QTL associated with performance and carcass traits on chicken chromosomes 1, 3, and 4
dc.typeArtigo


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