Nonalcoholic fatty liver disease and metabolic syndrome in postmenopausal women

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade Federal de Ouro Preto (UFOP)
dc.contributorUniversidade Federal de São João del-Rei (UFSJ)
dc.creatorRodrigues, Marcio H. [UNESP]
dc.creatorBruno, Anderson S. [UNESP]
dc.creatorNahas-Neto, Jorge [UNESP]
dc.creatorSantos, Maria Emilia S.
dc.creatorNahás, Eliana Aguiar Petri [UNESP]
dc.date2014-12-03T13:10:33Z
dc.date2014-12-03T13:10:33Z
dc.date2014-05-01
dc.date.accessioned2023-09-09T09:56:13Z
dc.date.available2023-09-09T09:56:13Z
dc.identifierhttp://dx.doi.org/10.3109/09513590.2013.875992
dc.identifierGynecological Endocrinology. New York: Informa Healthcare, v. 30, n. 5, p. 325-329, 2014.
dc.identifier0951-3590
dc.identifierhttp://hdl.handle.net/11449/112244
dc.identifier10.3109/09513590.2013.875992
dc.identifierWOS:000334743400001
dc.identifier4155170574788417
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8761876
dc.descriptionNonalcoholic fatty liver disease (NAFLD) is considered the most common cause of chronic liver disease in the Western countries. NAFLD includes a spectrum ranging from a simple steatosis to a nonalcoholic steatohepatitis (NASH) which is defined by the presence of inflammatory infiltrate, cellular necrosis, hepatocyte ballooning, and fibrosis and cirrhosis that can eventually develop into hepatocellular carcinoma. Studies emphasize the role of insulin resistance, oxidative stress, pro-inflammatory cytokines, adipokines in the development and progression of NAFLD. It seems to be independently associated with type II diabetes mellitus, increased triglycerides, decreased HDL-cholesterol, abdominal obesity and insulin resistance. These findings are in accordance with the criteria used in the diagnosis of metabolic syndrome (MetS). Here, we will discuss the current knowledge on the epidemiology, pathophysiology and diagnosis of NAFLD and the association of metabolic syndrome in postmenopausal women.
dc.descriptionSao Paulo State Univ, Botucatu Med Sch, Dept Gynecol & Obstet, Sao Paulo, Brazil
dc.descriptionUniv Fed Ouro Preto, Dept Gynecol & Obstet, Ouro Preto, MG, Brazil
dc.descriptionUniv Fed Sao Joao del Rei, Lab Metab Biochem, Divinopolis, MG, Brazil
dc.descriptionSao Paulo State Univ, Botucatu Med Sch, Dept Gynecol & Obstet, Sao Paulo, Brazil
dc.format325-329
dc.languageeng
dc.publisherInforma Healthcare
dc.relationGynecological Endocrinology
dc.relation1.453
dc.relation0,649
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectMenopause
dc.subjectmetabolic syndrome
dc.subjectnonalcoholic fatty liver disease
dc.titleNonalcoholic fatty liver disease and metabolic syndrome in postmenopausal women
dc.typeArtigo


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