Proposal to utilize simplified Swensen protocol in diagnosis of isolated pulmonary nodule

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorRibeiro, Sergio Marrone [UNESP]
dc.creatorRuiz, Raul Lopes [UNESP]
dc.creatorYoo, Hugo Hyung Bok [UNESP]
dc.creatorCataneo, Daniele Cristina [UNESP]
dc.creatorMaria Cataneo, Antonio Jose [UNESP]
dc.date2014-12-03T13:10:32Z
dc.date2014-12-03T13:10:32Z
dc.date2013-09-01
dc.date.accessioned2023-09-09T09:55:52Z
dc.date.available2023-09-09T09:55:52Z
dc.identifierhttp://dx.doi.org/10.1177/0284185113481695
dc.identifierActa Radiologica. London: Royal Soc Medicine Press Ltd, v. 54, n. 7, p. 757-764, 2013.
dc.identifier0284-1851
dc.identifierhttp://hdl.handle.net/11449/112223
dc.identifier10.1177/0284185113481695
dc.identifierWOS:000323511400008
dc.identifier3228294827229620
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8761855
dc.descriptionBackground: The problem of diagnosing whether a solitary pulmonary nodule is benign or malignant is even greater in developing countries due to a higher prevalence of infectious diseases. These infections generate a large number of patients who are generally asymptomatic and with a pulmonary nodule that cannot be accurately defined as having benign or malignant etiology.Purpose: To verify the percentages of benign versus malignant non-calcified nodules, the length of time after contrast agent injection is spiral computed tomography (CT) most sensitive and specific, and whether three postcontrast phases are necessary.Material and Methods: We studied 23 patients with solitary pulmonary nodules identified on chest radiographs or CT. Spiral scans were obtained with Swensen protocol, but at 3, 4, and 5 min after contrast injection onset. Nodules were classified as benign or malignant by histopathological examination or by an absence or presence of growth after 2 years of follow-up CT.Results: Of the 23 patients studied, 18 (78.2%) showed a final diagnosis of benign and five (21.7%) malignant nodules. Despite the small sample size, we obtained results similar to those of Swensen et al., with 80.0% sensitivity, 55.5% specificity, and 60.8% accuracy. Four minutes gave the greatest mean enhancement in both malignant and benign lesions.Conclusion: Small non-calcified benign nodules were much more frequent than malignant nodules. The best time for dynamic contrast-enhanced CT density analysis was 4 min postcontrast. As well as saving time and money, this simplified Swensen protocol with only precontrast and 4 min postcontrast phases also reduces patient exposure to ionizing radiation.
dc.descriptionUNESP Univ Estadual Paulista, Botucatu Med Sch, Dept Trop Dis & Diagnost Imaging, Botucatu, SP, Brazil
dc.descriptionUNESP Univ Estadual Paulista, Botucatu Med Sch, Dept Surg, Botucatu, SP, Brazil
dc.descriptionUNESP Univ Estadual Paulista, Botucatu Med Sch, Dept Internal Med, Botucatu, SP, Brazil
dc.descriptionUNESP Univ Estadual Paulista, Botucatu Med Sch, Dept Trop Dis & Diagnost Imaging, Botucatu, SP, Brazil
dc.descriptionUNESP Univ Estadual Paulista, Botucatu Med Sch, Dept Surg, Botucatu, SP, Brazil
dc.descriptionUNESP Univ Estadual Paulista, Botucatu Med Sch, Dept Internal Med, Botucatu, SP, Brazil
dc.format757-764
dc.languageeng
dc.publisherRoyal Soc Medicine Press Ltd
dc.relationActa Radiologica
dc.relation1.823
dc.relation0,754
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectPulmonary nodule
dc.subjectlung CT
dc.subjectlung neoplasms
dc.subjectdiagnosis
dc.titleProposal to utilize simplified Swensen protocol in diagnosis of isolated pulmonary nodule
dc.typeArtigo


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