Infarct Size as Predictor of Systolic Functional Recovery after Myocardial Infarction

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorMinicucci, Marcos Ferreira [UNESP]
dc.creatorFarah, Elaine [UNESP]
dc.creatorFusco, Danieliso R. [UNESP]
dc.creatorCogni, Ana Lucia [UNESP]
dc.creatorGaiolla, Paula Schmidt Azevedo [UNESP]
dc.creatorOkoshi, Katashi [UNESP]
dc.creatorZanati, Silmeia G. [UNESP]
dc.creatorMatsubara, Beatriz Bojikian [UNESP]
dc.creatorPaiva, Sergio Alberto Rupp de [UNESP]
dc.creatorZornoff, Leonardo Antonio Mamede [UNESP]
dc.date2014-12-03T13:07:01Z
dc.date2014-12-03T13:07:01Z
dc.date2014-06-01
dc.date.accessioned2023-09-09T09:34:16Z
dc.date.available2023-09-09T09:34:16Z
dc.identifierhttp://dx.doi.org/10.5935/abc.20140051
dc.identifierArquivos Brasileiros De Cardiologia. Rio De Janeiro: Arquivos Brasileiros Cardiologia, v. 102, n. 6, p. 549-555, 2014.
dc.identifier0066-782X
dc.identifierhttp://hdl.handle.net/11449/111166
dc.identifier10.5935/abc.20140051
dc.identifierS0066-782X2014005000051
dc.identifierWOS:000339011700007
dc.identifierS0066-782X2014005000051.pdf
dc.identifierS0066-782X2014005000051-pt.pdf
dc.identifier1590971576309420
dc.identifier6990977122340795
dc.identifier5016839015394547
dc.identifier1213140801402647
dc.identifier7438704034471673
dc.identifier0000-0002-5843-6232
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8760849
dc.descriptionBackground: The effects of modern therapy on functional recovery after acute myocardial infarction (AMI) are unknown.Objectives: To evaluate the predictors of systolic functional recovery after anterior AMI in patients undergoing modern therapy (reperfusion, aggressive platelet antiaggregant therapy, angiotensin-converting enzyme inhibitors and beta-blockers).Methods: A total of 94 consecutive patients with AMI with ST-segment elevation were enrolled. Echocardiograms were performed during the in-hospital phase and after 6 months. Systolic dysfunction was defined as ejection fraction value < 50%.Results: In the initial echocardiogram, 64% of patients had systolic dysfunction. Patients with ventricular dysfunction had greater infarct size, assessed by the measurement of total and isoenzyme MB creatine kinase enzymes, than patients without dysfunction. Additionally, 24.5% of patients that initially had systolic dysfunction showed recovery within 6 months after AMI. Patients who recovered ventricular function had smaller infarct sizes, but larger values of ejection fraction and E-wave deceleration time than patients without recovery. At the multivariate analysis, it can be observed that infarct size was the only independent predictor of functional recovery after 6 months of AMI when adjusted for age, gender, ejection fraction and E-wave deceleration time.Conclusion: In spite of aggressive treatment, systolic ventricular dysfunction remains a frequent event after the anterior myocardial infarction. Additionally, 25% of patients show functional recovery. Finally, infarct size was the only significant predictor of functional recovery after six months of acute myocardial infarction.
dc.descriptionUniv Estadual Paulista, Fac Med Botucatu, Botucatu, SP, Brazil
dc.descriptionUniv Estadual Paulista, Fac Med Botucatu, Botucatu, SP, Brazil
dc.format549-555
dc.languageeng
dc.publisherArquivos Brasileiros Cardiologia
dc.relationArquivos Brasileiros de Cardiologia
dc.relation1.318
dc.rightsAcesso aberto
dc.sourceWeb of Science
dc.subjectMyocardial Infarction
dc.subjectHeart Failure
dc.subjectVentricular Dysfunction
dc.subjectRecovery of Function
dc.titleInfarct Size as Predictor of Systolic Functional Recovery after Myocardial Infarction
dc.typeArtigo


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