| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Saad, W. A. | |
| dc.creator | Luiz, A. C. | |
| dc.creator | Camargo, LAA | |
| dc.creator | Menani, José Vanderlei | |
| dc.creator | Renzi, Antonio | |
| dc.creator | Silveira, JEN | |
| dc.date | 2014-05-20T15:20:08Z | |
| dc.date | 2016-10-25T17:53:11Z | |
| dc.date | 2014-05-20T15:20:08Z | |
| dc.date | 2016-10-25T17:53:11Z | |
| dc.date | 1993-09-01 | |
| dc.date.accessioned | 2017-04-05T23:24:06Z | |
| dc.date.available | 2017-04-05T23:24:06Z | |
| dc.identifier | Brazilian Journal of Medical and Biological Research. São Paulo: Associação Bras Divulg Cientifica, v. 26, n. 9, p. 999-1007, 1993. | |
| dc.identifier | 0100-879X | |
| dc.identifier | http://hdl.handle.net/11449/31477 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/31477 | |
| dc.identifier | WOS:A1993LY94100012 | |
| dc.identifier | http://www.scielo.br/scielo.php?script=sci_issues&pid=0100-879X&lng=en&nrm=iso | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/876017 | |
| dc.description | 1. The effect of lisinopril, a potent inhibitor of angiotensin converting enzyme (ACE), injected into the medial preoptic area (MPOA) on water intake was investigated in male Holtzman rats (200-250 g).2. Injection of lisinopril (2 mug/mul) into the MPOA abolished the water intake induced by subcutaneous (sc) injection of isoprenaline (100%) and water deprivation (90%) and drastically reduced the water intake induced by sc injection of polyethyleneglycol (60%). A small reduction of water intake induced by lisinopril was also observed 90 and 120 min after sc hypertonic saline (N = 10 for each group).3. These results suggest that central ACE activation, particularly in the MPOA, plays an important role in the dipsogenic responses induced by the agents studied. | |
| dc.language | eng | |
| dc.publisher | Associação Brasileira de Divulgação Científica (ABRADIC) | |
| dc.relation | Brazilian Journal of Medical and Biological Research | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | WATER INTAKE | |
| dc.subject | DEHYDRATION | |
| dc.subject | HYPOVOLEMIA | |
| dc.subject | ANGIOTENSIN-II | |
| dc.subject | LISINOPRIL | |
| dc.subject | MEDIAL PREOPTIC AREA | |
| dc.title | CENTRAL ANGIOTENSIN-CONVERTING ENZYME-BLOCKADE AND THIRST | |
| dc.type | Otro | |
