Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.creatorSoares, Luciana Arantes [UNESP]
dc.creatorSardi, Janaína De Cássia Orlandi [UNESP]
dc.creatorGullo, Fernanda Patrícia [UNESP]
dc.creatorPitangui, Nayla De Souza [UNESP]
dc.creatorScorzoni, Liliana [UNESP]
dc.creatorLeite, Fernanda Sangalli [UNESP]
dc.creatorMendes-Giannini, Maria José Soares [UNESP]
dc.creatorAlmeida, Ana Marisa Fusco [UNESP]
dc.date2014-10-01T13:08:55Z
dc.date2014-10-01T13:08:55Z
dc.date2013-12-01
dc.date.accessioned2023-09-09T09:19:29Z
dc.date.available2023-09-09T09:19:29Z
dc.identifierhttp://dx.doi.org/10.1590/S1517-83822014005000011
dc.identifierBrazilian Journal of Microbiology. Sociedade Brasileira de Microbiologia, v. 44, n. 4, p. 1035-1041, 2013.
dc.identifier1517-8382
dc.identifierhttp://hdl.handle.net/11449/110220
dc.identifier10.1590/S1517-83822014005000011
dc.identifierS1517-83822013000400003
dc.identifierWOS:000333959600003
dc.identifierS1517-83822013000400003.pdf
dc.identifier0000-0002-8059-0826
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8759919
dc.descriptionMillions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.
dc.descriptionUniversidade Estadual Paulista Faculdade de Ciências Farmacêuticas Departamento de Análises Clínicas
dc.descriptionUniversidade Estadual Paulista Faculdade de Ciências Farmacêuticas Departamento de Análises Clínicas
dc.format1035-1041
dc.languageeng
dc.publisherSociedade Brasileira de Microbiologia
dc.relationBrazilian Journal of Microbiology
dc.relation1.810
dc.relation0,630
dc.rightsAcesso aberto
dc.sourceSciELO
dc.subjectdermatophytes
dc.subjectfilamentous fungi
dc.subjectnatural products
dc.subjectsynthetic product
dc.titleAnti dermatophytic therapy: prospects for the discovery of new drugs from natural products
dc.typeArtigo


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