Use of Phthalimide and/or Sulphonamide Derivatives in the Treatment of Diseases Which Require Reducing the Tnf-alpha Levels and an Exogenous Source of Nitric Oxide, Phthalimide Derivatives, Sulphonamide Derivatives, and a Method for Obtaining a Sulphonamide Derivative

dc.contributorUniversidade Estadual de Campinas (UNICAMP)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade Federal do Rio de Janeiro (UFRJ)
dc.creatorSantos, Jean Leandro dos [UNESP]
dc.creatorChung, Man Chin
dc.creatorMoreira, Lima Lidia
dc.creatorFerreira, Costa Fernando
dc.creatorLanaro, Carolina
dc.date2014-09-02T13:14:18Z
dc.date2014-09-02T13:14:18Z
dc.date2012-02-24
dc.date2012-09-27
dc.date.accessioned2023-09-09T09:03:02Z
dc.date.available2023-09-09T09:03:02Z
dc.identifierhttp://worldwide.espacenet.com/publicationDetails/originalDocument?CC=US&FT=D&NR=2012245364A1
dc.identifierhttp://worldwide.espacenet.com/publicationDetails/originalDocument?CC=US&FT=D&NR=8338474B2
dc.identifierhttp://hdl.handle.net/11449/109082
dc.identifierINPI-PI0705396-7.pdf
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8758897
dc.descriptionProcesso: PI0705396-7
dc.descriptionNúmero de publicação: US2012245364 (A1)
dc.descriptionNúmero de publicação: US8338474 (B2)
dc.descriptionNúmero de aplicação: US201213404777
dc.descriptionPreparation and use of phthalimide and/or sulphonamide derivatives with nitric oxide donor properties, having activities in increasing gamma-globin gene expression and anti-inflammatory and analgesic activities, effective in the treatment of hematologic diseases which require reducing the TNF-[alpha] levels and an exogenous source of nitric oxide, such as sickle-cell disease. The functionalized phthalimide derivatives are designed from the prototypes thalidomide and hydroxyurea.
dc.languagepor
dc.publisherInstituto Nacional de Propriedade Industrial (INPI)
dc.rightsAcesso aberto
dc.sourceInstituto Nacional de Propriedade Industrial (INPI)
dc.titleUso de compostos derivados ftalimidicos e/ou sulfonamídicos no tratamento de doenças em que há a necessidade de diminuição dos níveis do fator TNF-alpha e a necessidade de uma fonte exógena de óxido nítrico, compostos derivados sulfonamídicos. Método de obtenção de um composto derivado sulfonamídico
dc.titleUse of Phthalimide and/or Sulphonamide Derivatives in the Treatment of Diseases Which Require Reducing the Tnf-alpha Levels and an Exogenous Source of Nitric Oxide, Phthalimide Derivatives, Sulphonamide Derivatives, and a Method for Obtaining a Sulphonamide Derivative
dc.typePatente


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