Incidence and risk factors related to SARS-CoV-2 infection, reinfection, and seroconversion among healthcare workers from a university hospital in Colombia.

dc.contributorQuintero Espinosa, Juliana
dc.contributorChaparro Narváez, Pablo Enrique
dc.contributorPinilla Roncancio, Mónica Viviana
dc.contributorRemolina, Camila I.
dc.contributorCaballero, Nohemí
dc.contributorSuárez Zamora, David A.
dc.contributorMoreno López, Sergio Mauricio
dc.contributorDurán, Daniela
dc.creatorNieto Rojas, María Alejandra
dc.date.accessioned2023-06-08T13:51:01Z
dc.date.accessioned2023-09-07T01:50:36Z
dc.date.available2023-06-08T13:51:01Z
dc.date.available2023-09-07T01:50:36Z
dc.date.created2023-06-08T13:51:01Z
dc.date.issued2023-05-27
dc.identifierhttp://hdl.handle.net/1992/67350
dc.identifierinstname:Universidad de los Andes
dc.identifierreponame:Repositorio Institucional Séneca
dc.identifierrepourl:https://repositorio.uniandes.edu.co/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8728721
dc.description.abstractBackground: The reported incidence of SARS-CoV-2 infection in healthcare workers (HCWs) is not consistent in the literature, ranging from 2% to 43%. This variability may be influenced by factors such as hospital policies, containment measures, and the emergence of more contagious variants. This study aimed to investigate the incidence and risk factors associated with SARS-CoV-2 infection and seroconversion among HCWs during different moments of the COVID-19 pandemic in a university hospital in Bogotá, Colombia. Methods: Data from the CoVIDA-FSFB project, a cohort comprising HCWs from Fundación Santa Fe de Bogotá (FSFB), a university hospital, were analyzed. The cohort included 420 HCWs that were followed in an active surveillance (from June 25, 2020 to April 30, 2021), followed by passive surveillance (from May 1, 2021 to March 16, 2022.). Incidence rates were estimated for SARS-CoV-2 infection, reinfection, and seroconversion for pre-and post-COVID-19 vaccination. Two different Cox Proportional-Hazards models were used to estimate factors related to infection and seroconversion during the active surveillance period. Results: The incidence rate of COVID-19 infection ranged between 16 to 52 cases per 1,000 person-month. SARS-CoV-2 reinfections were rare, ranging between less than 1 case to 13 cases per 1,000 person-month. The seroconversion rates ranged between 52 to 55 cases per 1,000 person-month. We also identified factors related to infection and seroconversion. High socioeconomic level was a protective factor for SARS-CoV-2 infection, while SARS-CoV-2 infection during the follow-up was the main factor associated with seroconversion. Conclusion: This study provides insights into the incidence and risk factors of SARS-CoV-2 infection among HCWs in a Colombian university hospital. The findings may offer valuable guidance for reducing virus spread within healthcare settings for these and other emergent diseases.
dc.languageeng
dc.publisherUniversidad de los Andes
dc.publisherMaestría en Epidemiología
dc.publisherFacultad de Medicina
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dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.titleIncidence and risk factors related to SARS-CoV-2 infection, reinfection, and seroconversion among healthcare workers from a university hospital in Colombia.
dc.typeTrabajo de grado - Maestría


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