Modelos matemáticos para entender el Síndrome de Guillain-Barré

dc.contributorBravo Vega, Carlos Andrés
dc.contributorArteaga Bejarano, José Ricardo
dc.contributorEspinoza, Baltazar
dc.contributorCordovez Alvarez, Juan Manuel
dc.contributorBIOMAC
dc.creatorGómez Patiño, Ana Gabriela
dc.date.accessioned2023-08-14T13:12:37Z
dc.date.accessioned2023-09-06T23:26:39Z
dc.date.available2023-08-14T13:12:37Z
dc.date.available2023-09-06T23:26:39Z
dc.date.created2023-08-14T13:12:37Z
dc.date.issued2023-06-05
dc.identifierhttp://hdl.handle.net/1992/69669
dc.identifierinstname:Universidad de los Andes
dc.identifierreponame:Repositorio Institucional Séneca
dc.identifierrepourl:https://repositorio.uniandes.edu.co/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8726523
dc.description.abstractEl síndrome de Guillain-Barré (SGB), es una polineuropatía aguda inmunomediada que es precedida por una infección que induce a una respuesta inmune. Los modelos matemáticos de dinámicas celulares para enfermedades infecciosas y autoinmunes nos permiten un acercamiento para entender esta enfermedad. Este trabajo de tesis proponen dos modelos epidemiológicos en el hospeador y uno de tratamiento , los cuales tienen un set de ecuaciones diferenciales El primero cuenta con tres variables que son las partículas virales (V), células Inmunes (I) y de Schwann (S) y el segundo cuenta cuatros variables que en adición están las inmunoglobulinas (Ig), finalmente se plantea un tercero que es el de plasmaféresis. Estos modelos permiten generar simulaciones del cambio de cada variable en un tiempo estimado de horas o días. Las simulaciones numéricas mostraron que los modelos muestra los cambios de la respuesta inmune y de las células de Schwann durante y después del proceso de infeccioso.
dc.languagespa
dc.publisherUniversidad de los Andes
dc.publisherMaestría en Ingeniería Biomédica
dc.publisherFacultad de Ingeniería
dc.publisherDepartamento de Ingeniería Biomédica
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dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.titleModelos matemáticos para entender el Síndrome de Guillain-Barré
dc.typeTrabajo de grado - Maestría


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