Otro
Binuclear cyclopalladated compounds with antitubercular activity: synthesis and characterization of [{Pd(C-2,N-dmba)(X)}(2)(mu-bpp)] (X = Cl, Br, NCO, N-3; bpp=1,3-bis(4-pyridyl)propane)
Registro en:
Journal of Coordination Chemistry. Abingdon: Taylor & Francis Ltd, v. 65, n. 8, p. 1434-1442, 2012.
0095-8972
10.1080/00958972.2012.673718
WOS:000304322800012
Autor
Moro, Antonio C.
Urbaczek, Ana C.
De Almeida, Eduardo T.
Pavan, Fernando R.
Leite, Clarice Q. F.
Netto, Adelino Vieira de Godoy
Mauro, Antonio Eduardo
Resumen
Reactions between [Pd(C-2,N-dmba)(mu-X)](2) (Hdmba = N,N-dimethylbenzylamine; X = Cl, Br, NCO, N-3) and 1,3-bis(4-pyridyl)propane (bpp) in 1 : 1 molar ratio at room temperature resulted in the binuclear compounds [{Pd(C-2,N-dmba)(X)}(2)(mu-bpp)] (X = Cl (1), Br (2), NCO (3), N-3 (4)), which were characterized by elemental analyses, infrared (IR), H-1- and C-13{H-1}-NMR spectroscopies, and thermogravimetric analysis. The IR and NMR data of 1-4 were consistent with the presence of bridging bpp. The thermal stability order of the complexes was 4 > 3 > 2 > 1. Compounds 1-4 and bpp were tested against Mycobacterium tuberculosis and their MIC values were determined. Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)