Effect of Ionic Liquid on the Determination of Aromatic Amines as Contaminants in Hair Dyes by Liquid Chromatography Coupled to Electrochemical Detection

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorLizier, Thiago Mescoloto
dc.creatorZanoni, Maria Valnice Boldrin
dc.date2014-05-20T14:19:33Z
dc.date2016-10-25T17:41:08Z
dc.date2014-05-20T14:19:33Z
dc.date2016-10-25T17:41:08Z
dc.date2012-07-01
dc.date.accessioned2017-04-05T22:31:45Z
dc.date.available2017-04-05T22:31:45Z
dc.identifierMolecules. Basel: Mdpi Ag, v. 17, n. 7, p. 7961-7979, 2012.
dc.identifier1420-3049
dc.identifierhttp://hdl.handle.net/11449/25900
dc.identifierhttp://acervodigital.unesp.br/handle/11449/25900
dc.identifier10.3390/molecules17077961
dc.identifierWOS:000306752700025
dc.identifierWOS000306752700025.pdf
dc.identifier0000-0002-2296-1393
dc.identifierhttp://dx.doi.org/10.3390/molecules17077961
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/870731
dc.descriptionThe room temperature ionic liquid (IL) 1-butyl-3-methylimidazolium bis-(trifluorometanesulfonyl) imide BMIm[NTf2] was used as a novel medium for improvement of separation and quantization of 16 aromatic amines typically present as contaminants in consumer products and detected by HPLC coupled to an electrochemical detector. The aromatic amines, namely 4,4'-diaminodiphenylmethane, 4-chloroaniline, 2-methoxy-5-methyl-aniline, 3,3'-dimethylbenzidine, 2,4-diaminotoluidine, 2-chloro-4-nitroaniline, 4,4'-oxydianiline, aniline, 3,3'-dichlorobenzidine, benzidine, 4-aminobiphenyl, o-dianisidine, o-anisidine, o-toluidine, 4,4'-methylene-bis-2-chloroaniline and 2-naphthylamine are oxidized in methanol/BMIm[NTf2] at a potential around +0.68V to +0.93V vs. Ag/AgCl at a glassy carbon electrode, which is the base for their determination by HPLC/ED. Using the optimized conditions of methanol/BMIm[NTf2] 70: 30 (v/v) as mobile phase, flow-rate of 0.8 mL.min(-1), column CLC-ODS, E-ap = +1.0 V and T = 40 C analytical curves were constructed for each of the tested amines. Good linearity was obtained in the concentration range of 1.09 mg.L-1 to 217 mg.L-1, with excellent correlation coefficients. The limits of detection reached 0.021 mg.L-1 to 0.246 mg.L-1 and good relative standard deviations (RSD, n = 3) were obtained from the measurements. Satisfactory recovery for each aromatic amine was achieved, ranging from 95 to 103%. The developed method was successfully applied to determine six aromatic amines present as contaminants in commercial hair dye samples.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.languageeng
dc.publisherMdpi Ag
dc.relationMolecules
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectionic liquid in chromatography
dc.subjectBMIm[NTf2]
dc.subjectHPLC with electrochemistry detection
dc.subjecthair dye
dc.subjectcarcinogenic amines determination
dc.titleEffect of Ionic Liquid on the Determination of Aromatic Amines as Contaminants in Hair Dyes by Liquid Chromatography Coupled to Electrochemical Detection
dc.typeOtro


Este ítem pertenece a la siguiente institución