dc.contributor | Goyeneche-Patiño, Diego Andrés | |
dc.contributor | Pinilla-León, Juan Carlos | |
dc.contributor | Barrera-Rivera, Jennifer | |
dc.creator | Cruz-Barajas, María Camila | |
dc.date.accessioned | 2023-03-31T16:51:12Z | |
dc.date.accessioned | 2023-09-06T19:13:52Z | |
dc.date.available | 2023-03-31T16:51:12Z | |
dc.date.available | 2023-09-06T19:13:52Z | |
dc.date.created | 2023-03-31T16:51:12Z | |
dc.date.issued | 2022-12-12 | |
dc.identifier | T 35.22 C789d | |
dc.identifier | https://repositorio.udes.edu.co/handle/001/8267 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8702110 | |
dc.description.abstract | El distemper canino, es una enfermedad viral altamente contagiosa y patogénica debido a sus
altas tasas de morbilidad y mortalidad. El virus es del género Morbillivirus y hace parte de la
familia Paramyxoviridae.
La prevención es realizada por medio de la vacunación, al ser la respuesta inmune
individual y especifica no todos los caninos desarrollan títulos de anticuerpos IgM e IgG
protectivos, debido a esto, se presentan caninos vacunados con títulos de anticuerpos bajos por
una estimulación pobre de la actividad celular, encontrándose expuestos a contraer la
enfermedad. La falla vacunal se debe a una respuesta inmune insuficiente, el estatus sanitario del
animal y a un mal manejo vacunal. Debido a esto el objetivo principal de este trabajo es
determinar los títulos de anticuerpos anti-moquillo en caninos de Bucaramanga y su área
metropolitana.
Se tomaron muestras de sangre de 92 caninos mayores a 6 meses de edad con
antecedentes de vacunación contra moquillo. Y posteriormente mediante la técnica de
inmunoensayo enzimático indirecto (ELISA), se determinaron los títulos de anticuerpos IgG e
IgM contra al virus en suero. Adicionalmente se realizó una encuesta epidemiológica a los
propietarios, con el fin de caracterizar variables poblacionales y su posible relación con los
títulos de anticuerpos obtenidos.
Se determinó que, de los 92 caninos implementados en el estudio, 28/92 presentaron
títulos de anticuerpos IgG altos (31%), 55/92 presentaron títulos de anticuerpos IgG medios
(60%) y 9/92 presentaron títulos de anticuerpos IgG bajos (9%) con una asociación estadística
significativa con las variables poblacionales edad y refuerzo de vacunación. Los títulos de
anticuerpos IgM fueron clasificados en bajos/medios y altos, con un total de 79/92 caninos con
títulos de anticuerpos IgM altos (86%) y 13/92 caninos con títulos de anticuerpos IgM medios/
bajos (14%), la clasificación no tuvo asociación estadística con las variables | |
dc.description.abstract | Canine distemper is a highly contagious and pathogenic viral disease, due to its high morbidity
and mortality rates. The virus belongs to the Morbillivirus genus and Paramyxoviridae family.
Prevention is based on vaccination, since the immune response is individual and specific,
not all dogs develop protective IgM and IgG antibody titers, due to this, vaccinated dogs present
low antibody titers explained by poor stimulation of celular immunity and are exposed to
contracting the disease. Vaccine failure is the result of insufficient immune response, animal
health status and poor vaccination management. Therefore, the aim of this work is to determine
the titers of anti-distemper antibodies (IgG and IgM) in dogs from Bucaramanga and its
metropolitan area.
Blood from of 92 dogs older than 6 months of age with a history of vaccination against
distemper was taken. After serum extraction samples were analyzed using indirect enzyme
immunoassay (ELISA) technique. Additionally, an epidemiological survey was carried out to the
owners, in order to characterize population variables and their possible relationship with the
antibody titers obtained.
that the results showed that, out of the 92 canines implemented in the study, 28/92
presented high IgG antibody titers (30.43%), 55/92 presented medium IgG antibody titers
(59.78%) and 9/92 presented titers of low IgG antibodies (9.78%) with a significant statistical
association in the population variables age and vaccination reinforcement. IgM antibody titers
were classified as low/medium and high, with a total of 79/92 canines with high IgM antibody
titers (85.86%) and 13/92 canines with medium/low IgM antibody titers (14, 13%) without
significant statistical association. | |
dc.publisher | Universidad de Santander | |
dc.publisher | Bucaramanga | |
dc.publisher | Facultad de Ciencias Exactas, Naturales y Agropecuarias | |
dc.publisher | Bucaramanga, Colombia | |
dc.publisher | Medicina Veterinaria | |
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dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights | http://purl.org/coar/access_right/c_abf2 | |
dc.rights | Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) | |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.rights | Derechos Reservados - Universidad de Santander, 2022. Al consultar y hacer uso de este recurso, está aceptando las condiciones de uso establecidas por los autores. | |
dc.title | Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana | |
dc.type | Trabajo de grado - Pregrado | |