Desenlaces materno-perinatales de la población obstétrica con infección por SARS COV-2 durante los Años 2020 y 2021 en un hospital de tercer nivel del departamento de Caldas, Colombia.

dc.contributorArango Gómez, Fernando
dc.contributorHenao Navarro, Leidy Diana
dc.creatorRestrepo Mejía, Juan David
dc.date2023-04-27T16:32:56Z
dc.date2023-04-27T16:32:56Z
dc.date2023-04-27
dc.date.accessioned2023-09-06T18:26:44Z
dc.date.available2023-09-06T18:26:44Z
dc.identifierhttps://repositorio.ucaldas.edu.co/handle/ucaldas/18919
dc.identifierUniversidad de Caldas
dc.identifierRepositorio Institucional Universidad de Caldas
dc.identifierhttps://repositorio.ucaldas.edu.co/
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8697464
dc.descriptionIlustraciones
dc.descriptionspa:La aparición del virus SARS-CoV-2 y la posterior pandemia por COVID-19 ha afectado al mundo entero durante los últimos 3 años, con más de 531 millones de casos y 6,2 millones de muertes. En Colombia se han notificado más de 6 millones de casos y 139.867 muertes de las cuales el 39,23% corresponden a fallecimientos de mujeres (1). Se ha identificado que las mujeres embarazadas que adquieren una infección por SARS- CoV2 presentan una mayor morbilidad y mortalidad. Se ha establecido por ejemplo, mayor riesgo de enfermedad grave, ingreso a unidades de cuidados intensivos, necesidad de ventilación invasiva y hasta 1,5 veces más probabilidades de muerte. Con respecto a la posible asociación a resultados perinatales adversos, se ha descrito un incremento en los casos de preeclampsia, parto prematuro, muerte fetal, bajo peso al nacer e ingreso en unidades de cuidados intensivos neonatales (2,3). Esta investigación buscó determinar la asociación entre la infección materna por SARS-CoV- 2 y el desarrollo de morbilidad materno-perinatal en un hospital de tercer nivel de Caldas Colombia, durante el periodo de pandemia desde el año 2020 a 2021, así como la realización de una caracterización de la población mediante la descripción de características sociodemográficas y clínicas. Para alcanzar los objetivos propuestos y contrastar la hipótesis de trabajo se desarrolló un estudio de cohortes retrospectivo, cuya población objeto de estudio está conformada por un grupo de pacientes embarazadas con diagnóstico de infección por SARS-CoV-2 (diagnóstico establecido mediante el hallazgo de una prueba PCR positiva) y un grupo control conformado por pacientes en quienes se descartó dicha infección. Se conformaron entonces dos grupos de pacientes: 81 pacientes con infección por SARS- COV2 confirmada y 168 sin infección. No se encontraron diferencias significativas en la edad o el estado civil entre los dos grupos. Se encontró una mayor proporción de pacientes con un nivel socioeconómico bajo en el grupo de mujeres sin infección por SARS-COV2. La mayoría de las pacientes del grupo SARS-COV2 positivo tenían algún tipo de seguro médico. El nivel educativo fue mayor en el grupo SARS-COV2 positivo, pero la diferencia no fue estadísticamente significativa. Los métodos de inducción de parto más utilizados fueron la oxitocina y el misoprostol. Se identificó que en el grupo de pacientes con infección por SARS-CoV-2 hay una mayor tasa de cesáreas y un mayor riesgo desarrollar preeclampsia y diabetes gestacional.
dc.descriptioneng:The emergence of the SARS-CoV-2 virus and the subsequent COVID-19 pandemic have affected the entire world in the last 3 years, with more than 531 million cases and 6.2 million deaths. In Colombia, more than 6 million cases and 139,867 deaths have been reported, of which 39.23% correspond to deaths of women (1). Pregnant women who acquire a SARS-CoV2 infection have been identified as having increased morbidity and mortality. For example, an increased risk of severe disease, admission to intensive care units, the need for invasive ventilation, and up to 1.5 times more odds of death have been established. Regarding the possible association with adverse perinatal outcomes, an increase in cases of preeclampsia, premature delivery, stillbirth, low birth weight, and admission to neonatal intensive care units has been described (2,3). This research sought to determine the association between maternal SARS-CoV-2 infection and the development of maternal-perinatal morbidity in a tertiary level hospital in Caldas Colombia, during the pandemic period from 2020 to 2021, as well as conducting of a characterization of the population through the description of sociodemographic and clinical characteristics. To achieve the proposed objectives and contrast the working hypothesis, a retrospective cohort study was developed, whose population under study is made up of a group of pregnant patients diagnosed with SARS-CoV-2 infection (diagnosis established by finding a positive PCR test) and a control group made up of patients in whom said infection was ruled out. Two groups of patients were then formed: 81 patients with confirmed SARS-COV2 infection and 168 without infection. No significant differences in age or marital status were found between the two groups. A higher proportion of patients with a low socioeconomic level was found in the group of women without SARS-COV2 infection. Most of the patients in the SARS-COV2 positive group had some form of health insurance. The educational level was higher in the SARS-COV2 positive group, but the difference was not statistically significant. The most used labor induction methods were oxytocin and misoprostol. It was identified that in the group of patients with SARS-CoV-2 infection there is a higher rate of cesarean sections and a higher risk of developing preeclampsia and gestational diabetes. Keywords: SARS-CoV-2, COVID-19, Pregnancy, maternal-perinatal outcomes, preterm delivery, neonatal resuscitation, preeclampsia, postpartum hemorrhage, gestational diabetes, hypothyroidism, hyperthyroidism.
dc.descriptionResumen / Abstract / Introducción / Antecedentes y planteamiento del problema / Pregunta de investigación / Objetivo general / Objetivos específicos / Hipótesis / Hipótesis alterna / Hipótesis nula / Metodología / Tipo de estudio / Población y muestra / Criterios de inclusión / Criterios de exclusión: / Proceso Metodológico / Análisis Estadístico / Resultados / Análisis Descriptivo / Análisis bivariado / Discusión / Conclusiones / Bibliografía
dc.descriptionEspecialización médico - quirúrgica
dc.descriptionEspecialista en Obstetricia y Ginecología
dc.descriptionMaterno Fetal
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dc.languageeng
dc.languagespa
dc.publisherFacultad de Ciencias para la Salud
dc.publisherManizales
dc.publisherEspecialización en Obstetricia y Ginecología
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dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.subjectSARS-CoV-2
dc.subjectCOVID-19
dc.subjectEmbarazo
dc.subjectPreeclampsia
dc.subjectHipotiroidismo
dc.subjectHipertiroidismo
dc.subjectDesenlaces materno-perinatales,
dc.subjectHemorragia postparto,
dc.subjectDiabetes gestacional
dc.subjectCiencias médicas
dc.titleDesenlaces materno-perinatales de la población obstétrica con infección por SARS COV-2 durante los Años 2020 y 2021 en un hospital de tercer nivel del departamento de Caldas, Colombia.
dc.typeTrabajo de grado - Especialización
dc.typehttp://purl.org/coar/resource_type/c_bdcc
dc.typeText
dc.typeinfo:eu-repo/semantics/masterThesis
dc.typehttps://purl.org/redcol/resource_type/TM
dc.typeinfo:eu-repo/semantics/publishedVersion


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