Extruded vesicles of dioctadecyldimethylammonium bromide and chloride investigated by light scattering and cryogenic transmission electron microscopy

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorlopes, Antonio
dc.creatorEdwards, Katarina
dc.creatorFeitosa, Eloi
dc.date2014-05-20T14:02:32Z
dc.date2016-10-25T17:09:09Z
dc.date2014-05-20T14:02:32Z
dc.date2016-10-25T17:09:09Z
dc.date2008-06-15
dc.date.accessioned2017-04-05T21:27:48Z
dc.date.available2017-04-05T21:27:48Z
dc.identifierJournal of Colloid and Interface Science. San Diego: Academic Press Inc. Elsevier B.V., v. 322, n. 2, p. 582-588, 2008.
dc.identifier0021-9797
dc.identifierhttp://hdl.handle.net/11449/22041
dc.identifierhttp://acervodigital.unesp.br/handle/11449/22041
dc.identifier10.1016/j.jcis.2008.03.015
dc.identifierWOS:000256161500027
dc.identifierhttp://dx.doi.org/10.1016/j.jcis.2008.03.015
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/867507
dc.descriptionCombined dynamic and static light scattering (DLS, SLS) and cryogenic transmission electron microscopy (cryo-TEM) were used to investigate extruded cationic vesicles of dioctadecyldimethylammonium chloride and bromide (DODAX, X being Cl- or Br-). In salt-free dispersions the mean hydrodynamic diameter, D-h, and the weight average molecular weight, M-w, are larger for DODAB than for DODAC vesicles, and both D-h and M-w increase with the diameter (phi) of the extrusion filter. NaCl (NaBr) decreases (increases) the DODAB (DODAC) vesicle size, reflecting the general trend of DODAB to assemble as larger vesicles than DODAC. The polydispersity index is lower than 0.25, indicating the dispersions are rather polydisperse. Cryo-TEM micrographs show that the smaller vesicles are spherical while the larger ones are oblong or faceted, and the vesicle samples are fairly polydisperse in size and morphology. They also indicate that the vesicle size increases with phi and DODAB assembles as larger vesicles than DODAC. Lens-shaped vesicles were observed in the extruded preparations. Both light scattering and cryo-TEM indicate that the vesicle size is larger or smaller than phi when phi is smaller or larger than the optimal phi* approximate to 200 nm. (C) 2008 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherAcademic Press Inc. Elsevier B.V.
dc.relationJournal of Colloid and Interface Science
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDODAB
dc.subjectDODAC
dc.subjectCationic vesicle
dc.subjectextruded vesicle
dc.subjectlens-shaped vesicle
dc.subjectlight scattering
dc.subjectCryo-TEM
dc.titleExtruded vesicles of dioctadecyldimethylammonium bromide and chloride investigated by light scattering and cryogenic transmission electron microscopy
dc.typeOtro


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