Apoptosis in tongue squamous cell carcinoma and its correlation with clinically occult cervical metastasis

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorMolina, Fernando D.
dc.creatorBertollo, Eny M. G.
dc.creatorAssis, Claudiane M.
dc.creatorFalleiros, Luis R.
dc.creatorCampos, Silvana G. P.
dc.creatorManiglia, Jose V.
dc.creatorTaboga, Sebastiao R.
dc.date2014-05-20T14:01:01Z
dc.date2016-10-25T17:08:21Z
dc.date2014-05-20T14:01:01Z
dc.date2016-10-25T17:08:21Z
dc.date2008-10-01
dc.date.accessioned2017-04-05T21:24:30Z
dc.date.available2017-04-05T21:24:30Z
dc.identifierMicron. Oxford: Pergamon-Elsevier B.V. Ltd, v. 39, n. 7, p. 910-914, 2008.
dc.identifier0968-4328
dc.identifierhttp://hdl.handle.net/11449/21561
dc.identifierhttp://acervodigital.unesp.br/handle/11449/21561
dc.identifier10.1016/j.micron.2007.11.006
dc.identifierWOS:000259422800020
dc.identifier0000-0002-0970-4288
dc.identifierhttp://dx.doi.org/10.1016/j.micron.2007.11.006
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/867114
dc.descriptionSquamous cell carcinoma of the tongue is one of the most common head and neck cancer. Treatment in the early stages is still controversial. This study aims to correlate the apoptosis rate of primary tongue cancer with cervical node metastasis, found in the histopathological studies of specimens obtained from neck dissections or during clinical follow-up. Twenty patients, 65% males, mean age 64.5 years, without clinical evidence of cervical metastasis was included. Eighty-five percent were smokers and 40% were alcohol abusers. Mann-Whitney test was used for statistical analysis (p <= 0.05). Five patients with clinically occult cervical metastases had metastasis in the histopathological specimens (25%) occult metastasis. The mean apoptosis rate in patients without cervical metastasis was 9.43%. Twenty-five percent of the patients had occult cervical metastasis. High apoptosis rate in tongue cancer, even in the absence of palpable neck nodes, correlates with the presence of occult metastasis. (C) 2007 Elsevier Ltd. All rights reserved.
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageeng
dc.publisherPergamon-Elsevier B.V. Ltd
dc.relationMicron
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectApoptosis
dc.subjecttongue cancers
dc.subjectoccult metastasis
dc.subjectsquamous cell carcinoma
dc.titleApoptosis in tongue squamous cell carcinoma and its correlation with clinically occult cervical metastasis
dc.typeOtro


Este ítem pertenece a la siguiente institución