Destruction of Leishmania Mexicana Amazonensis promastigotes by normal human serum

dc.creatorBarral Netto, Manoel
dc.creatorRoters, Silene B.
dc.creatorSherlock, Ítalo Rodrigues de Araújo
dc.creatorReed, S. G.
dc.date.accessioned2019-06-19T17:14:47Z
dc.date.accessioned2023-09-05T14:48:35Z
dc.date.available2019-06-19T17:14:47Z
dc.date.available2023-09-05T14:48:35Z
dc.date.created2019-06-19T17:14:47Z
dc.date.issued1987
dc.identifierBARRAL NETTO, Manoel et al. Destruction of Leishmania Mexicana Amazonensis promastigotes by normal human serum. American Journal of Tropical Medicine and Hygiene, v. 37, n. 1, p. 53-56, 1987.
dc.identifier0002-9637
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/33592
dc.identifier10.4269/ajtmh.1987.37.53
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8662511
dc.description.abstractFresh normal human serum was observed to have a lethal effect on Leishmania mexicana amazonensis promastigotes obtained from laboratory-bred Lutzomyia longipalpis or on promastigotes grown in liquid culture medium, inoculated with the same isolates. Heat inactivation abolished the Leishmania lytic activity from the sera. Resistance of culture promastigotes to lysis by normal human serum was investigated in three isolates of L. m. amazonensis. Development of resistance (up to 7%) was found in only one isolate, obtained from the bone marrow in a human case of visceral leishmaniasis.
dc.languageeng
dc.publisherAmerican Society of Tropical Medicine and Hygiene
dc.rightsrestricted access
dc.titleDestruction of Leishmania Mexicana Amazonensis promastigotes by normal human serum
dc.typeArticle


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