Phosphorylation of Histone H3S10 in Animal Chromosomes: Is There a Uniform Pattern?

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorSotero-Caio, C. G.
dc.creatorde Souza, M. J.
dc.creatorCabral-de-Mello, Diogo Cavalcanti
dc.creatorBrasileiro-Vidal, A. C.
dc.creatorGuerra, M.
dc.date2014-05-20T13:55:10Z
dc.date2016-10-25T17:04:58Z
dc.date2014-05-20T13:55:10Z
dc.date2016-10-25T17:04:58Z
dc.date2011-01-01
dc.date.accessioned2017-04-05T21:12:19Z
dc.date.available2017-04-05T21:12:19Z
dc.identifierCytogenetic and Genome Research. Basel: Karger, v. 135, n. 2, p. 111-117, 2011.
dc.identifier1424-8581
dc.identifierhttp://hdl.handle.net/11449/19734
dc.identifierhttp://acervodigital.unesp.br/handle/11449/19734
dc.identifier10.1159/000330918
dc.identifierWOS:000296388400004
dc.identifierhttp://dx.doi.org/10.1159/000330918
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/865532
dc.descriptionPhosphorylation of serine 10 in histone H3 (H3S10ph) has been extensively analyzed and appears to be a conserved chromatin change associated with chromosome condensation in different eukaryotic organisms. In this work, we report the distribution of H3S10ph during meiosis in monocentric and holokinetic chromosomes of 6 insect species and in mitotic chromosomes of 7 mammalian species, aiming to investigate the labeling patterns in phylogenetically distant groups. The results indicated a very similar phosphorylation timing and distribution pattern among insects. The sex chromosomes of insects analyzed were always undercondensed and hypophosphorylated. Similarly, the micro chromosomes of the bug Pachylis aff pharaonis were also undercondensed and hypophosphorylated. Holokinetic chromosomes of bugs and monocentric chromosomes of grasshoppers and beetles displayed identical phosphorylation pattern in spite of the difference in the centromere type. Among mammals, a uniform chromosome phosphorylation was observed in marsupials, whereas bat chromosomes displayed a longitudinal banding pattern. These data indicate that, in general, the intensity of H3S10 phosphorylation in animal chromosomes is variable among the distinct chromosome types and associated with the degree of chromatin condensation at metaphase, but it may vary between different groups of animals. Copyright (C) 2011 S. Karger AG, Basel
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherKarger
dc.relationCytogenetic and Genome Research
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectChromosome condensation
dc.subjectH3 phosphorylation
dc.subjectHolokinetic chromosomes
dc.subjectMicro chromosomes
dc.subjectSex chromosomes
dc.titlePhosphorylation of Histone H3S10 in Animal Chromosomes: Is There a Uniform Pattern?
dc.typeOtro


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