Protection of calves against Haemonchus placei and Haemonchus contortus after immunization with gut membrane proteins from H. contortus

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorBassetto, C. C.
dc.creatorSilva, B. F.
dc.creatorNewlands, G. F. J.
dc.creatorSmith, W. D.
dc.creatorAmarante, Alessandro Francisco Talamini do
dc.date2014-05-20T13:53:02Z
dc.date2016-10-25T17:03:47Z
dc.date2014-05-20T13:53:02Z
dc.date2016-10-25T17:03:47Z
dc.date2011-07-01
dc.date.accessioned2017-04-05T21:07:59Z
dc.date.available2017-04-05T21:07:59Z
dc.identifierParasite Immunology. Malden: Wiley-blackwell, v. 33, n. 7, p. 377-381, 2011.
dc.identifier0141-9838
dc.identifierhttp://hdl.handle.net/11449/18918
dc.identifierhttp://acervodigital.unesp.br/handle/11449/18918
dc.identifier10.1111/j.1365-3024.2011.01295.x
dc.identifierWOS:000292760100003
dc.identifierhttp://dx.doi.org/10.1111/j.1365-3024.2011.01295.x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/864943
dc.descriptionA vaccine containing integral membrane glycoproteins from the intestine of Haemonchus contortus was evaluated in four groups of nine worm-free calves challenged with either 8000 H. contortus or Haemonchus placei infective larvae. Vaccinates received 50 mu g of the antigen and 1 mg QuilA adjuvant three times 21 days apart, while the controls got adjuvant alone. The calves were challenged 7 days after the last immunization and killed for worm counts 43 days later. Immunization resulted in high titre antibodies against the vaccine antigens and significant reduction in egg output and worm numbers of both challenge species, compared with control calves. It was concluded that vaccination of calves with native parasite gut membrane glycoproteins obtained from H. contortus conferred protection against both H. placei and H. contortus.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherWiley-Blackwell
dc.relationParasite Immunology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcattle
dc.subjectHaemonchus contortus
dc.subjectHaemonchus placei
dc.subjectparasitic gastroenteritis
dc.subjectvaccine
dc.titleProtection of calves against Haemonchus placei and Haemonchus contortus after immunization with gut membrane proteins from H. contortus
dc.typeOtro


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