Functional morphology of adult female Culex quinquefasciatus midgut during blood digestion

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorOkuda, K.
dc.creatorCaroci, A. D.
dc.creatorRibolla, PEM
dc.creatorde Bianchi, A. G.
dc.creatorBijovsky, A. T.
dc.date2014-05-20T13:52:42Z
dc.date2016-10-25T17:03:36Z
dc.date2014-05-20T13:52:42Z
dc.date2016-10-25T17:03:36Z
dc.date2002-06-01
dc.date.accessioned2017-04-05T21:07:23Z
dc.date.available2017-04-05T21:07:23Z
dc.identifierTissue & Cell. Edinburgh: Churchill Livingstone, v. 34, n. 3, p. 210-219, 2002.
dc.identifier0040-8166
dc.identifierhttp://hdl.handle.net/11449/18824
dc.identifierhttp://acervodigital.unesp.br/handle/11449/18824
dc.identifier10.1016/S0040-8166(02)00032-0
dc.identifierWOS:000178197200009
dc.identifierhttp://dx.doi.org/10.1016/S0040-8166(02)00032-0
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/864863
dc.descriptionThe adult female Culex quinquefasciatus midgut comprises a narrow anterior and a dilated posterior region, with epithelia composed of a monolayer of adjacent epithelial cells joined at the apical portion by septate junctions. Densely packed apical microvilli and an intricate basal labyrinth characterise each cell pole. Our morphological studies suggest that, during blood digestion, the anterior midgut region also participates in an initial absorptive stage which is probably related to the intake of water, salts and other small molecules. This activity peaked by 6 h after bloodmeal feeding (ABF) and ended approximately 18 h ABF, when the peritrophic membrane was already formed. After this time, absorption only occurred in the posterior region, with morphologic and biochemical evidence of high synthetic activity related to the secretion of proteases. Chymotrypsin, elastase, aminopeptidase, and trypsin reached their maximum activity at around 36 h ABF. Digestion products were apparently absorbed and transported to the basal labyrinth, from where they should be released to the hemolymph. At 72 h ABF, proteolysis had already ended and protein levels had returned to those observed before blood meal. The epithelium of the posterior region, however, did not return to its initial morphology, appearing quite disorganised. Additionally, from 48 h ABF onwards some epithelial cells showed morphological signals of apoptosis. (C) 2002 Elsevier B.V. Ltd. All rights reserved.
dc.languageeng
dc.publisherChurchill Livingstone
dc.relationTissue & Cell
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCulex quinquefasciatus
dc.subjectmidgut
dc.subjectmosquito
dc.subjectultrastructure
dc.subjectprotease
dc.titleFunctional morphology of adult female Culex quinquefasciatus midgut during blood digestion
dc.typeOtro


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