Comparative cytogenetic mapping of Sox2 and Sox14 in cichlid fishes and inferences on the genomic organization of both genes in vertebrates

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorMazzuchelli, Juliana
dc.creatorYang, Fengtang
dc.creatorKocher, Thomas D.
dc.creatorMartins, Cesar
dc.date2014-05-20T13:52:21Z
dc.date2016-10-25T17:03:27Z
dc.date2014-05-20T13:52:21Z
dc.date2016-10-25T17:03:27Z
dc.date2011-07-01
dc.date.accessioned2017-04-05T21:06:48Z
dc.date.available2017-04-05T21:06:48Z
dc.identifierChromosome Research. Dordrecht: Springer, v. 19, n. 5, p. 657-667, 2011.
dc.identifier0967-3849
dc.identifierhttp://hdl.handle.net/11449/18713
dc.identifierhttp://acervodigital.unesp.br/handle/11449/18713
dc.identifier10.1007/s10577-011-9225-4
dc.identifierWOS:000292929300008
dc.identifierhttp://dx.doi.org/10.1007/s10577-011-9225-4
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/864787
dc.descriptionTo better understand the genomic organization and evolution of Sox genes in vertebrates, we cytogenetically mapped Sox2 and Sox14 genes in cichlid fishes and performed comparative analyses of their orthologs in several vertebrate species. The genomic regions neighboring Sox2 and Sox14 have been conserved during vertebrate diversification. Although cichlids seem to have undergone high rates of genomic rearrangements, Sox2 and Sox14 are linked in the same chromosome in the Etroplinae Etroplus maculatus that represents the sister group of all remaining cichlids. However, these genes are located on different chromosomes in several species of the sister group Pseudocrenilabrinae. Similarly, the ancestral synteny of Sox2 and Sox14 has been maintained in several vertebrates, but this synteny has been broken independently in all major groups as a consequence of karyotype rearrangements that took place during the vertebrate evolution.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.languageeng
dc.publisherSpringer
dc.relationChromosome Research
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCichlidae
dc.subjectgenome evolution
dc.subjectmolecular cytogenetics
dc.subjectchromosome
dc.titleComparative cytogenetic mapping of Sox2 and Sox14 in cichlid fishes and inferences on the genomic organization of both genes in vertebrates
dc.typeOtro


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