| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Seito, L. N. | |
| dc.creator | Mazaro, R. | |
| dc.creator | Di Stasi, L. C. | |
| dc.date | 2014-05-20T13:49:01Z | |
| dc.date | 2016-10-25T17:01:38Z | |
| dc.date | 2014-05-20T13:49:01Z | |
| dc.date | 2016-10-25T17:01:38Z | |
| dc.date | 2002-03-01 | |
| dc.date.accessioned | 2017-04-05T21:00:16Z | |
| dc.date.available | 2017-04-05T21:00:16Z | |
| dc.identifier | Phytotherapy Research. W Sussex: John Wiley & Sons Ltd, v. 16, n. 2, p. 193-196, 2002. | |
| dc.identifier | 0951-418X | |
| dc.identifier | http://hdl.handle.net/11449/17448 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/17448 | |
| dc.identifier | 10.1002/ptr.932 | |
| dc.identifier | WOS:000174798100019 | |
| dc.identifier | http://dx.doi.org/10.1002/ptr.932 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/863928 | |
| dc.description | Austroplenckia populnea (Reiss.) Lund. is a Brazilian Cerrado plant belonging to the Celastraceae family. Hexane and methanol extracts of leaves were investigated for their antiulcerogenic (ethanol and indomethacin/bethanecol induced gastric damage) and analgesic (writhing and tail-flick tests) activities in mice. Acute toxic effects also were evaluated. Oral administration of both extracts at a dose of 1000 mg/kg significantly reduced the total area of the lesion, the relative area of lesion and the ulcerative index in ethanol-induced gastric damage, but both extracts were inactive in the indomethacin/bethanecol-induced gastric damage test. A dose dependent effect was determined with the hexane extract in the ethanol-induced lesions test. The hexane and methanol extracts reduced the number of contortions in the writhing test, but both extracts were inactive in the tail-flick immersion test. Copyright (C) 2002 John Wiley Sons, Ltd. | |
| dc.language | eng | |
| dc.publisher | Wiley-Blackwell | |
| dc.relation | Phytotherapy Research | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | medicinal plants | |
| dc.subject | antiulcerogenic | |
| dc.subject | analgesic | |
| dc.subject | Celastraceae | |
| dc.subject | Austroplenckia populnea | |
| dc.title | Antiulcerogenic and analgesic effects of the Austroplenckia populnea extracts in mice | |
| dc.type | Otro | |
