Effectiveness of two disinfectant solutions and microwave irradiation in disinfecting complete dentures contaminated with methicillin-resistant Staphylococcus aureus

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorAltieri, Karen Tereza
dc.creatorSanita, Paula Volpato
dc.creatorMachado, Ana Lucia
dc.creatorGiampaolo, Eunice Teresinha
dc.creatorPavarina, Ana Claudia
dc.creatorVergani, Carlos Eduardo
dc.date2014-05-20T13:46:36Z
dc.date2016-10-25T17:00:17Z
dc.date2014-05-20T13:46:36Z
dc.date2016-10-25T17:00:17Z
dc.date2012-03-01
dc.date.accessioned2017-04-05T20:55:29Z
dc.date.available2017-04-05T20:55:29Z
dc.identifierJournal of The American Dental Association. Chicago: Amer Dental Assoc, v. 143, n. 3, p. 270-277, 2012.
dc.identifier0002-8177
dc.identifierhttp://hdl.handle.net/11449/16509
dc.identifierhttp://acervodigital.unesp.br/handle/11449/16509
dc.identifierWOS:000301619600018
dc.identifierhttp://jada.ada.org/content/143/3/270.long
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/863288
dc.descriptionBackground. Methicillin-resistant Staphylococcus aureus (MRSA) biofilm on dentures can be aspirated, thus causing infections such as aspiration pneumonia. The authors evaluated the efficacy of two disinfectant solutions and microwave irradiation in disinfecting complete dentures contaminated with MRSA.Methods. The authors contaminated 36 simulated complete dentures with MRSA and divided them into four equal groups: a positive control group consisting of dentures that were not disinfected; a group that soaked in 1 percent sodium hypochlorite for 10 minutes; a group that soaked in 2 percent chlorhexidine gluconate for 10 minutes; and a group that underwent microwave irradiation at 650 watts for three minutes. The authors quantified colony counts and evaluated the long-term effectiveness of disinfection.Results. All dentures from the control group showed substantial microbial growth on the plates (6.24 log(10) colony-forming units per milliliter). The authors observed no evidence of microbial growth on plates of any disinfected dentures. After seven days' incubation, the authors observed broth turbidity in all beakers containing the dentures disinfected with 1 percent sodium hypochlorite.Conclusions. Soaking in chlorhexidine gluconate solution and microwave irradiation resulted in complete disinfection of all dentures contaminated with MRSA in both the short and the long term. Soaking in sodium hypochlorite solution was effective only as a short-term disinfectant.Clinical Implications. Microwave irradiation and 2 percent chlorhexidine gluconate may have a disinfective application in dental offices and institutions in which denture wearers are treated, thus improving the longevity and quality of life of patients and reducing the burden of disease caused by MRSA.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.languageeng
dc.publisherAmer Dental Assoc
dc.relationJournal of the American Dental Association
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMethicillin-resistant Staphylococcus aureus (MRSA)
dc.subjectcomplete dentures
dc.subjectmicrowave irradiation
dc.subjectdisinfection
dc.subjectdisinfectants
dc.titleEffectiveness of two disinfectant solutions and microwave irradiation in disinfecting complete dentures contaminated with methicillin-resistant Staphylococcus aureus
dc.typeOtro


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