Low-level laser therapy (670 nm) on viability of random skin flap in rats

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorBossini, Paulo Sergio
dc.creatorFangel, Renan
dc.creatorHabenschus, Rafael Malfara
dc.creatorRenno, Ana Claudia
dc.creatorBenze, Benedito
dc.creatorAntonio, Jose
dc.creatorBenatti Neto, Carlos
dc.creatorParizotto, Nivaldo Antonio
dc.date2014-05-20T13:46:04Z
dc.date2016-10-25T16:59:54Z
dc.date2014-05-20T13:46:04Z
dc.date2016-10-25T16:59:54Z
dc.date2009-03-01
dc.date.accessioned2017-04-05T20:54:07Z
dc.date.available2017-04-05T20:54:07Z
dc.identifierLasers In Medical Science. Artington: Springer London Ltd, v. 24, n. 2, p. 209-213, 2009.
dc.identifier0268-8921
dc.identifierhttp://hdl.handle.net/11449/16267
dc.identifierhttp://acervodigital.unesp.br/handle/11449/16267
dc.identifier10.1007/s10103-008-0551-5
dc.identifierWOS:000263673700014
dc.identifierhttp://dx.doi.org/10.1007/s10103-008-0551-5
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/863101
dc.descriptionThis study investigated the effects of 670 nm laser, at different fluences, on the viability of skin flap in rats. One hundred male animals were used. The animals were divided into control group; group treated with 3 J/cm(2); group treated with 6 J/cm(2); group treated with 12 J/cm(2) and group treated with 24 J/cm(2). The skin flap was made on the backs of all animals studied, with a plastic sheet interposed between the flap and the donor site. Laser irradiation was done immediately after the surgery and on days 1, 2, 3 and 4 after surgery. The percentage of necrosis of the flap was calculated at the 7th postoperative day. Additionally, a sample of each flap was collected to enable us to count the blood vessels. Treated animals showed a statistically significant smaller area of necrosis than did the control group. The necrosis in the treated groups was 41.82% (group 2), 36.51% (group 3), 29.45% (group 4) and 20.37% (group 5). We also demonstrated that laser irradiation at 670 nm, at all doses used, had a stimulatory effect on angiogenesis. Our study showed that the 670 nm laser was efficient to increase the viability of the skin flap, at all fluences used, with a tendency of reaching better results at higher doses.
dc.languageeng
dc.publisherSpringer London Ltd
dc.relationLasers in Medical Science
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectLaser therapy
dc.subjectMicrocirculation
dc.subjectNecrosis
dc.subjectSurgical flaps
dc.titleLow-level laser therapy (670 nm) on viability of random skin flap in rats
dc.typeOtro


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