| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Lima, Adriano Fonseca | |
| dc.creator | Rosetti Lessa, Fernanda Campos | |
| dc.creator | Gasparoto Mancini, Maria Nadir | |
| dc.creator | Hebling, Josimeri | |
| dc.creator | de Souza Costa, Carlos Alberto | |
| dc.creator | Marchi, Giselle Maria | |
| dc.date | 2013-09-30T18:32:15Z | |
| dc.date | 2014-05-20T13:44:49Z | |
| dc.date | 2016-10-25T16:58:57Z | |
| dc.date | 2013-09-30T18:32:15Z | |
| dc.date | 2014-05-20T13:44:49Z | |
| dc.date | 2016-10-25T16:58:57Z | |
| dc.date | 2010-04-01 | |
| dc.date.accessioned | 2017-04-05T20:50:22Z | |
| dc.date.available | 2017-04-05T20:50:22Z | |
| dc.identifier | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology. New York: Mosby-elsevier, v. 109, n. 4, p. E70-E76, 2010. | |
| dc.identifier | 1079-2104 | |
| dc.identifier | http://hdl.handle.net/11449/15722 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/15722 | |
| dc.identifier | 10.1016/j.tripleo.2009.12.020 | |
| dc.identifier | WOS:000275746200035 | |
| dc.identifier | http://dx.doi.org/10.1016/j.tripleo.2009.12.020 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/862652 | |
| dc.description | Objectives. The objectives of this study were to evaluate the transdentinal cytotoxicity of 10% and 16% carbamide peroxide gel (CP), as well as the ability of the antioxidant, 10% sodium ascorbate (SA), to protect the odontoblasts in culture.Study design. Human dentin discs of 0.5-mm thickness were obtained and were placed into artificial pulp chambers. MDPC-23 odontoblastlike cells were seeded on pulp surface of the discs and the following groups were established: G1-No Treatment (control), G2-10% SA/6hs, G3-10%/CP6hs, G4-10%SA/6hs+10%CP/6hs, G5-16%CP/6hs, and G6-10%SA/6hs+16%CP/6hs. The cell viability was measured by the MTT assay.Results. In groups where 16% CP was used, decreased cell viability was observed. Conversely, the application of 10% SA on the dentin discs, before the use of the CP, reduced the cytotoxic effects of these products on cells.Conclusions. The 16% CP cause a significant decrease in MDPC-23 cell viability and 10% SA was able to partially prevent the toxic effects of CP. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: e70-e76) | |
| dc.description | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) | |
| dc.description | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) | |
| dc.language | eng | |
| dc.publisher | Mosby-elsevier | |
| dc.relation | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.title | Transdentinal protective role of sodium ascorbate against the cytopathic effects of H2O2 released from bleaching agents | |
| dc.type | Otro | |
