Microbiota associated with chronic osteomyelitis of the jaws

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorJardim Júnior, Élerson Gaetti
dc.creatorFardin, Angélica Cristiane
dc.creatorGaetti-Jardim, Ellen Cristina
dc.creatorCastro, Alvimar Lima de
dc.creatorSchweitzer, Christiane Marie
dc.creatorAvila-Campos, Mario Julio
dc.date2013-09-30T18:31:13Z
dc.date2014-05-20T13:44:41Z
dc.date2013-09-30T18:31:13Z
dc.date2014-05-20T13:44:41Z
dc.date2010-12-01
dc.date.accessioned2017-04-05T20:49:57Z
dc.date.available2017-04-05T20:49:57Z
dc.identifierBrazilian Journal of Microbiology. Sociedade Brasileira de Microbiologia, v. 41, n. 4, p. 1056-1064, 2010.
dc.identifier1517-8382
dc.identifierhttp://hdl.handle.net/11449/15663
dc.identifier10.1590/S1517-83822010000400025
dc.identifierS1517-83822010000400025
dc.identifierWOS:000286432800025
dc.identifierS1517-83822010000400025.pdf
dc.identifier0000-0001-9561-8281
dc.identifierhttp://dx.doi.org/10.1590/S1517-83822010000400025
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/862598
dc.descriptionChronic osteomyelitis of maxilla and mandible is rare in industrialized countries and its occurrence in developing countries is associated with trauma and surgery, and its microbial etiology has not been studied thoroughly. The aim of this investigation was to evaluate the microbiota associated with osteomyelitis of mandible or maxilla from some Brazilian patients. After clinical and radiographic evaluation, samples of bone sequestra, purulent secretion, and biopsies of granulomatous tissues from twenty-two patients with chronic osteomyelitis of mandible and maxilla were cultivated and submitted for pathogen detection by using a PCR method. Each patient harbored a single lesion. Bacterial isolation was performed on fastidious anaerobe agar supplemented with hemin, menadione and horse blood for anaerobes; and on tryptic soy agar supplemented with yeast extract and horse blood for facultative bacteria and aerobes. Plates were incubated in anaerobiosis and aerobiosis, at 37ºC for 14 and 3 days, respectively. Bacteria were cultivated from twelve patient samples; and genera Actinomyces, Fusobacterium, Parvimonas, and Staphylococcus were the most frequent. By PCR, bacterial DNA was detected from sixteen patient samples. The results suggest that cases of chronic osteomyelitis of the jaws are usually mixed anaerobic infections, reinforcing the concept that osteomyelitis of the jaws are mainly related to microorganisms from the oral environment, and periapical and periodontal infections may act as predisposing factors.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageeng
dc.publisherSociedade Brasileira de Microbiologia
dc.relationBrazilian Journal of Microbiology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectosteomyelitis
dc.subjectbacteria
dc.subjectanaerobes
dc.subjectmaxilla
dc.subjectmandible
dc.titleMicrobiota associated with chronic osteomyelitis of the jaws
dc.typeOtro


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