Otro
Occurrence of yeasts, pseudomonads and enteric bacteria in the oral cavity of patients undergoing head and neck radiotherapy
Registro en:
Brazilian Journal of Microbiology. Sociedade Brasileira de Microbiologia, v. 42, n. 3, p. 1047-1055, 2011.
1517-8382
10.1590/S1517-83822011000300024
S1517-83822011000300024
WOS:000297756800024
S1517-83822011000300024.pdf
0000-0001-9561-8281
Autor
Jardim Júnior, Élerson Gaetti
Ciesielski, Francisco Isaak Nicolas
Sousa, Fátima Regina Nunes de
Nwaokorie, Francisca
Schweitzer, Christiane Marie
Avila-Campos, Mario Júlio
Resumen
The aim of this study was to evaluate the occurrence of yeasts, pseudomonads and enteric bacteria in the oral cavity of patients undergoing radiotherapy (RT) for treatment of head and neck cancer. Fifty patients receiving RT were examined before, during and 30 days after RT. Saliva, mucosa, and biofilm samples were collected and microorganisms were detected by culture and polymerase chain reaction (PCR). The most prevalent yeasts in patients submitted to RT were Candida albicans, C. tropicalis, C. krusei, C. glabrata and C. parapsilosis. Citrobacter, Enterobacter, Enterococcus, Klebsiella, Proteus, and Pseudomonas were the most frequently cultivated bacteria. Before RT, targeted bacteria were cultivated from 22.2% of edentulous patients and 16.6% of dentate patients; 30 days after RT, these microorganisms were recovered from 77.8% edentulous and 46.8% dentate patients. By PCR, these microorganisms were detected from all edentulous patients, 78.1% of dentate patients. The presence of Gram-negative enteric roads and fungi was particularly frequent in patients presenting mucositis level III or IV. Modifications in the oral environment due to RT treatment seem to facilitate the colonization of oral cavity by members of family Enterobacteriaceae, genera Enterococcus and Candida. Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)