Urinary fluoride output in children following the use of a dual-fluoride varnish formulation

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorKaneshiro Olympio, Kelly Polido
dc.creatorda Silva Cardoso, Vanessa Eid
dc.creatorBorro Bijella, Maria Fernanda
dc.creatorPessan, Juliano Pelim
dc.creatorDelbem, Alberto Carlos Botazzo
dc.creatorRabelo Buzalaf, Marilia Afonso
dc.date2013-09-30T18:30:39Z
dc.date2014-05-20T13:44:15Z
dc.date2013-09-30T18:30:39Z
dc.date2014-05-20T13:44:15Z
dc.date2009-05-01
dc.date.accessioned2017-04-05T20:49:09Z
dc.date.available2017-04-05T20:49:09Z
dc.identifierJournal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 17, n. 3, p. 179-183, 2009.
dc.identifier1678-7757
dc.identifierhttp://hdl.handle.net/11449/15505
dc.identifierWOS:000266689200009
dc.identifierS1678-77572009000300009.pdf
dc.identifier0000-0002-8159-4853
dc.identifierhttp://dx.doi.org/10.1590/S1678-77572009000300009
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/862492
dc.descriptionObjective: This study evaluated the bioavailability of fluoride after topical application of a dual-fluoride varnish commercially available in Brazil, when compared to Duraphat T. Material and methods: The urinary fluoride output was evaluated in seven 5-year-old children after application of the fluoride varnishes, in two different phases. In the first phase (I), children received topical application of the fluoride varnish Duofluorid XII (2.92% fluorine, calcium fluoride + 2.71% fluorine, sodium fluoride, FGM (TM)). After 1-month interval (phase II), the same amount (0.2 mL) of the fluoride varnish Duraphat (2.26% fluorine, sodium fluoride, Colgate T) was applied. Before each application all the volunteers brushed their teeth with placebo dentifrice for 7 days. Urinary collections were carried out 24 h prior up to 48 h after the applications. Fluoride intake from the diet was also estimated. Fluoride concentration in diet samples and urine was analyzed with the fluoride ion-specific electrode and a miniature calomel reference electrode coupled to a potentiometer. Data were tested by ANOVA and Tukey's post hoc test (p < 0.05). Results: There were significant differences in the urinary fluoride output between phases I and II. The use of Duofluorid XII did not significantly increase the urinary fluoride output, when compared to baseline levels. The application of Duraphat caused a transitory increase in the urinary fluoride output, returning to baseline levels 48 h after its use. Conclusions: The tested varnish formulation, which has been shown to be effective in in vitro studies, also can be considered safe.
dc.languageeng
dc.publisherUniversidade de São Paulo (USP), Faculdade de Odontologia de Bauru
dc.relationJournal of Applied Oral Science
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectFluorine
dc.subjectVarnishes
dc.subjectUrine
dc.subjectToxicity
dc.subjectChildren
dc.titleUrinary fluoride output in children following the use of a dual-fluoride varnish formulation
dc.typeOtro


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