Effects of different types of physical exercise on the staining of parvalbumin-positive neurons in the hippocampal formation of rats with epilepsy

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.contributorUniv Mogi das Cruzes
dc.creatorArida, Ricardo Mario [UNIFESP]
dc.creatorScorza, Carla Alessandra [UNIFESP]
dc.creatorScorza, Fulvio Alexandre [UNIFESP]
dc.creatorSilva, Sergio Gomes da
dc.creatorNaffah-Mazzacoratti, Maria da Graca [UNIFESP]
dc.creatorCavalheiro, Esper Abrao [UNIFESP]
dc.date.accessioned2016-01-24T13:48:43Z
dc.date.accessioned2023-09-04T19:06:17Z
dc.date.available2016-01-24T13:48:43Z
dc.date.available2023-09-04T19:06:17Z
dc.date.created2016-01-24T13:48:43Z
dc.date.issued2007-05-09
dc.identifierProgress in Neuro-psychopharmacology & Biological Psychiatry. Oxford: Pergamon-Elsevier B.V., v. 31, n. 4, p. 814-822, 2007.
dc.identifier0278-5846
dc.identifierhttp://repositorio.unifesp.br/handle/11600/29747
dc.identifier10.1016/j.pnpbp.2007.01.021
dc.identifierWOS:000246931200004
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8622780
dc.description.abstractEffects of exercise in animals with epilepsy have been demonstrated. To investigate whether the type of physical activity, voluntary or forced, would promote different morphological changes in hippocampal formation we performed an immunocytochemical study using the parvalbumin (PV) distribution as a marker. Control rats and rats with epilepsy were submitted to a voluntary (wheel running) and forced (treadmill) exercise for 10 days (acute physical exercise) or 45 days (chronic physical exercise). It was observed in normal rats a higher number of PV-positive cells in the hilus of dentate gyrus (DG) in the voluntary and forced exercise groups (acute and chronic physical exercise), when compared to the control group. in animals with epilepsy the number of PV-positive cells and staining intensity of PV-fibers in the hilus was significantly higher only in the acute physical exercise (voluntary and forced). These findings demonstrate that acute physical exercise, both voluntary and forced results in increased number of PV-positive cells and staining intensity of PV-fibers in the hilus of rats with epilepsy and the occurrence of these changes takes place only in the early phase of epilepsy. (c) 2007 Published by Elsevier Inc.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationProgress in Neuro-psychopharmacology & Biological Psychiatry
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.rightsAcesso restrito
dc.subjectepilepsy
dc.subjecthippocampal formation
dc.subjectparvalbumin
dc.subjectphysical exercise
dc.subjectrat
dc.titleEffects of different types of physical exercise on the staining of parvalbumin-positive neurons in the hippocampal formation of rats with epilepsy
dc.typeResenha


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